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6MGN

mouse Id1 (51-104) - human hE47 (348-399) complex

Summary for 6MGN
Entry DOI10.2210/pdb6mgn/pdb
DescriptorTranscription factor E2-alpha, DNA-binding protein inhibitor ID-1 (3 entities in total)
Functional Keywordsdna-binding protein inhibitor id-1, transcription factor e2-alpha isoform e47 [homo sapiens], dna binding protein
Biological sourceHomo sapiens (Human)
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Total number of polymer chains2
Total formula weight11726.70
Authors
Benezra, R.,Pavletich, N.P.,Gall, A.-L.,Goldgur, Y. (deposition date: 2018-09-14, release date: 2019-09-18, Last modification date: 2023-10-11)
Primary citationWojnarowicz, P.M.,Lima E Silva, R.,Ohnaka, M.,Lee, S.B.,Chin, Y.,Kulukian, A.,Chang, S.H.,Desai, B.,Garcia Escolano, M.,Shah, R.,Garcia-Cao, M.,Xu, S.,Kadam, R.,Goldgur, Y.,Miller, M.A.,Ouerfelli, O.,Yang, G.,Arakawa, T.,Albanese, S.K.,Garland, W.A.,Stoller, G.,Chaudhary, J.,Norton, L.,Soni, R.K.,Philip, J.,Hendrickson, R.C.,Iavarone, A.,Dannenberg, A.J.,Chodera, J.D.,Pavletich, N.,Lasorella, A.,Campochiaro, P.A.,Benezra, R.
A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29:62-75.e7, 2019
Cited by
PubMed: 31577956
DOI: 10.1016/j.celrep.2019.08.073
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.901 Å)
Structure validation

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