PDB: 205 件ウェブページステータス検索Chemie searchBIRD

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7N8K	LINE-1 endonuclease domain complex with Mg 分子名称: ACETATE ION, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... 著者 Korolev, S, Miller, I. 登録日 2021-06-15 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease. Nucleic Acids Res., 49, 2021
7N8S	LINE-1 endonuclease domain complex with DNA 分子名称: DNA (5'-D(*CP*CP*TP*TP*AP*AP*AP*AP*AP*GP*GP*AP*GP*CP*T)-3'), DNA (5'-D(*GP*CP*TP*CP*CP*TP*TP*TP*TP*TP*AP*AP*GP*GP*A)-3'), LINE-1 retrotransposable element ORF2 protein 著者 Korolev, S, Miller, I. 登録日 2021-06-15 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease. Nucleic Acids Res., 49, 2021
7NXV	Crystal structure of the complex of DNase I/G-actin/PPP1R15A_582-621 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Yan, Y, Ron, D. 登録日 2021-03-19 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
7NZM	Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Yan, Y, Hardwick, S, Ron, D. 登録日 2021-03-24 公開日 2021-09-29 最終更新日 2021-10-20 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
7LPH	APE1 Mn-bound product complex with abasic ribonucleotide DNA 分子名称: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-R(P*N)-D(P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), ... 著者 Freudenthal, B.D, Hoitsma, N.M. 登録日 2021-02-11 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucker. Comput Struct Biotechnol J, 19, 2021
7LPJ	APE1 Mn-bound phosphorothioate substrate complex with abasic ribonucleotide DNA 分子名称: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-R(P*(YA4))-D(P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA-(apurinic or apyrimidinic site) lyase, ... 著者 Freudenthal, B.D, Hoitsma, N.M. 登録日 2021-02-11 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucker. Comput Struct Biotechnol J, 19, 2021
7LPG	APE1 product complex with abasic ribonucleotide DNA 分子名称: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-R(P*N)-D(P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), ... 著者 Freudenthal, B.D, Hoitsma, N.M. 登録日 2021-02-11 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucker. Comput Struct Biotechnol J, 19, 2021
7LPI	APE1 phosphorothioate substrate complex with abasic ribonucleotide DNA 分子名称: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-R(P*(YA4))-D(P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Hoitsma, N.M. 登録日 2021-02-11 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucker. Comput Struct Biotechnol J, 19, 2021
7AX1	Crystal structure of the human CCR4-CAF1 complex 分子名称: CCR4-NOT transcription complex subunit 6, CCR4-NOT transcription complex subunit 7, MAGNESIUM ION 著者 Chen, Y, Khazina, E, Weichenrieder, O. 登録日 2020-11-09 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex. Nucleic Acids Res., 49, 2021
6VX4	Density-fitted Model Structure of Antibody Variable Domains of TyTx11 in Complex with Typhoid Toxin 分子名称: Cytolethal distending toxin subunit B, Pertussis like toxin subunit B, Pertussis toxin-like subunit ArtA, ... 著者 Nguyen, T, Song, J. 登録日 2020-02-21 公開日 2021-02-24 最終更新日 2021-07-14 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Mechanisms of typhoid toxin neutralization by antibodies targeting glycan receptor binding and nuclease subunits. Iscience, 24, 2021
7CD6	mAPE1-recessed dsDNA product complex 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*AP*C)-3'), DNA-(apurinic or apyrimidinic site) endonuclease 著者 Liu, T.C, Hsiao, Y.Y. 登録日 2020-06-18 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling. Nat Commun, 12, 2021
7CD5	mAPE1-blunt-ended dsDNA product complex 分子名称: DNA(5'-D(*CP*GP*TP*AP*AP*TP*AP*CP*G)-3'), DNA-(apurinic or apyrimidinic site) endonuclease 著者 Liu, T.C, Hsiao, Y.Y. 登録日 2020-06-18 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling. Nat Commun, 12, 2021
7CNE	Crystal Structure of Sphingomyelinase C from Streptomyces griseocarneus 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SUCCINIC ACID, Sphingomyelinase C 著者 Murayama, K, Fujisawa, I, Sugimori, D. 登録日 2020-07-31 公開日 2020-10-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the high thermal stability and optimum pH of sphingomyelinase C from Streptomyces griseocarneus. J.Biosci.Bioeng., 131, 2021
6W4T	APE1 Y269A phosphorothioate substrate complex with abasic DNA 分子名称: DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*(48Z)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Hoitsma, N.M. 登録日 2020-03-11 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop. Nucleic Acids Res., 48, 2020
6W4I	APE1 Y269A product complex with abasic DNA 分子名称: DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Freudenthal, B.D, Hoitsma, N.M. 登録日 2020-03-10 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop. Nucleic Acids Res., 48, 2020
6W3N	APE1 exonuclease substrate complex D148E 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(C7R))-3'), ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-09 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
6W2P	APE1 endonuclease product complex L104R 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-06 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
6W3Q	APE1 exonuclease substrate complex L104R 分子名称: CALCIUM ION, DNA-(apurinic or apyrimidinic site) lyase, GCTGATGCG(C7R), ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-09 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
6W3U	APE1 exonuclease substrate complex R237C 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-09 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
6W3L	APE1 exonuclease substrate complex wild-type 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA-(apurinic or apyrimidinic site) lyase, ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-09 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
6W0Q	APE1 endonuclease product complex D148E 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-02 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
6W43	APE1 AP-endonuclease product complex R237C 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-10 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
6LPM	Crystal structure of AP endonuclease from Deinococcus radioduran 分子名称: Exodeoxyribonuclease III 著者 Zhao, Y, He, Y. 登録日 2020-01-11 公開日 2020-05-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural and Functional Characterization of a Unique AP Endonuclease From Deinococcus radiodurans . Front Microbiol, 11, 2020
6RVZ	Crystal structure of ANGEL2, a 2',3'-cyclic phosphatase, in complex with adenosine-2',3'-vanadate 分子名称: ADENOSINE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Kroupova, A, Jinek, M. 登録日 2019-06-03 公開日 2020-05-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity. Science, 369, 2020
6RW0	Crystal structure of ANGEL2, a 2',3'-cyclic phosphatase 分子名称: GLYCEROL, MAGNESIUM ION, POTASSIUM ION, ... 著者 Kroupova, A, Jinek, M. 登録日 2019-06-03 公開日 2020-05-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity. Science, 369, 2020

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