6W3U

APE1 exonuclease substrate complex R237C

Summary for 6W3U

• Entry DOI: 10.2210/pdb6w3u/pdb
• Descriptor: DNA (5'-D(P*TP*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(C7R))-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (9 entities in total)
• Functional Keywords: nuclease, abasic site, dna repair, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 75327.04

Authors

Freudenthal, B.D.,Whitaker, A.M. (deposition date: 2020-03-09, release date: 2020-06-10, Last modification date: 2023-10-18)

• Primary citation: Whitaker, A.M.,Stark, W.J.,Flynn, T.S.,Freudenthal, B.D.; Molecular and structural characterization of disease-associated APE1 polymorphisms.; DNA Repair (Amst.), 91-92:102867-102867, 2020; PubMed: 32454397; DOI: 10.1016/j.dnarep.2020.102867

Experimental method

X-RAY DIFFRACTION (2.4 Å)