7N8K

LINE-1 endonuclease domain complex with Mg

Summary for 7N8K

Entry DOI	10.2210/pdb7n8k/pdb
Descriptor	LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ACETATE ION, ... (5 entities in total)
Functional Keywords	endonuclease, non-ltr retrotransposon, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	55200.67
Authors	Korolev, S.,Miller, I. (deposition date: 2021-06-15, release date: 2021-10-13, Last modification date: 2023-10-18)
Primary citation	Miller, I.,Totrov, M.,Korotchkina, L.,Kazyulkin, D.N.,Gudkov, A.V.,Korolev, S. Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease. Nucleic Acids Res., 49:11350-11366, 2021 Cited by PubMed: 34554261 DOI: 10.1093/nar/gkab826 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.01 Å)

Structure validation