7NXV

Crystal structure of the complex of DNase I/G-actin/PPP1R15A_582-621

Summary for 7NXV

• Entry DOI: 10.2210/pdb7nxv/pdb
• Descriptor: Actin, alpha skeletal muscle, intermediate form, Deoxyribonuclease-1, Protein phosphatase 1 regulatory subunit 15A, ... (7 entities in total)
• Functional Keywords: hydrolase regulator, protein phosphatase 1 regulatory unit, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 153536.84

Authors

Yan, Y.,Ron, D. (deposition date: 2021-03-19, release date: 2021-09-29, Last modification date: 2024-01-31)

• Primary citation: Yan, Y.,Harding, H.P.,Ron, D.; Higher-order phosphatase-substrate contacts terminate the integrated stress response.; Nat.Struct.Mol.Biol., 28:835-846, 2021; PubMed: 34625748; DOI: 10.1038/s41594-021-00666-7

Experimental method

X-RAY DIFFRACTION (2.55 Å)