PDB: 492 resultsInfo pagesStatus searchChemie searchBIRD

---

3HKR	Crystal Structure of Glutathione Transferase Pi Y108V Mutant Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... Authors: Parker, L.J. Deposit date: 2009-05-25 Release date: 2009-09-22 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci., 18, 2009
3KMN	Crystal Structure of the Human Apo GST Pi C47S/Y108V Double Mutant Descriptor: CALCIUM ION, CARBONATE ION, Glutathione S-transferase P, ... Authors: Parker, L.J. Deposit date: 2009-11-11 Release date: 2010-03-23 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Diuretic drug binding to human glutathione transferase P1-1: potential role of CYS101 revealed in the double mutant C47S/Y108V to be published
3KM6	Crystal Structure of the Human GST Pi C47S/Y108V Double Mutant in Complex with the Ethacrynic Acid-Glutathione Conjugate Descriptor: CALCIUM ION, ETHACRYNIC ACID, GLUTATHIONE, ... Authors: Parker, L.J. Deposit date: 2009-11-10 Release date: 2010-03-23 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V. J.Mol.Recognit., 24
1MD3	A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to alanine Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase Authors: Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W. Deposit date: 2002-08-06 Release date: 2002-08-21 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1 J.Biol.Chem., 278, 2003
3EE2	Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole Descriptor: GLUTATHIONE, Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, ... Authors: Oakley, A.J. Deposit date: 2008-09-04 Release date: 2008-09-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D(2) synthase Eur.J.Med.Chem., 45, 2010
1OKT	X-ray Structure of Glutathione S-Transferase from the Malarial Parasite Plasmodium falciparum Descriptor: FORMIC ACID, GLUTATHIONE S-TRANSFERASE Authors: Fritz-Wolf, K, Becker, A, Rahlfs, s, Harwaldt, P, Schirmer, R.H, Kabsch, W, Becker, K. Deposit date: 2003-07-29 Release date: 2003-11-20 Last modified: 2019-07-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-Ray Structure of Glutathione S-Transferase from the Malarial Parasite Plasmodium Falciparum Proc.Natl.Acad.Sci.USA, 100, 2003
5AN1	Crystallographic structure of the Glutathione S-Transferase from Litopenaeus vannamei complexed with Glutathione Descriptor: GLUTATHIONE, GLUTATHIONE S-TRANSFERASE Authors: Juarez-Martinez, A.B, Sotelo-Mundo, R, Rudino-Pinera, E. Deposit date: 2015-09-02 Release date: 2016-10-12 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of a class-mu glutathione S-transferase from whiteleg shrimp Litopenaeus vannamei: structural changes in the xenobiotic binding H-site may alter the spectra of molecules bound. J. Biochem. Mol. Toxicol., 31, 2017
5AIS	Complex of human hematopoietic prostagandin D2 synthase (hH-PGDS) in complex with an active site inhibitor. Descriptor: 4-(dimethylamino)-N-[5-(1H-indol-4-yl)pyridin-3-yl]butanamide, GLUTATHIONE, HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE, ... Authors: Edfeldt, F, Evenas, J, Lepisto, M, Ward, A, Petersen, J, Wissler, L, Rohman, M, Sivars, U, Svensson, K, Perry, M, Feierberg, I, Zhou, X, Hansson, T, Narjes, F. Deposit date: 2015-02-17 Release date: 2015-06-03 Last modified: 2015-06-10 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Identification of Indole Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase (Hh-Pgds). Bioorg.Med.Chem.Lett., 25, 2015
3D0Z	Structural charcaterization of an engineered allosteric protein Descriptor: GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme Authors: Sagermann, M. Deposit date: 2008-05-02 Release date: 2009-02-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Using affinity chromatography to engineer and characterize pH-dependent protein switches. Protein Sci., 18, 2009
5AGY	CRYSTAL STRUCTURE OF A TAU CLASS GST MUTANT FROM GLYCINE Descriptor: 4-NITROPHENYL METHANETHIOL, GLUTATHIONE S-TRANSFERASE, PHOSPHATE ION, ... Authors: Axarli, I, Muleta, A.W, Vlachakis, D, Kossida, S, Kotzia, G, Dhavala, P, Papageorgiou, A.C, Labrou, N.E. Deposit date: 2015-02-04 Release date: 2015-12-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Directed Evolution of Tau Class Glutathione Transferases Reveals a Site that Regulates Catalytic Efficiency and Masks Cooperativity. Biochem.J., 473, 2016
3DD3	Crystal Structure of the Glutathione Transferase Pi enzyme in complex with the bifunctional inhibitor, Etharapta Descriptor: (eta6-benzene)ruthenium, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, ... Authors: Parker, L.J. Deposit date: 2008-06-05 Release date: 2009-04-21 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Rational design of an organometallic glutathione transferase inhibitor Angew.Chem.Int.Ed.Engl., 48, 2009
3F63	Crystal structure of a Delta class GST (adGSTD4-4) from Anopheles dirus, in complex with S-hexyl glutathione Descriptor: Glutathione transferase GST1-4, S-HEXYLGLUTATHIONE Authors: Wongsantichon, J, Robinson, R.C, Ketterman, A.J. Deposit date: 2008-11-05 Release date: 2009-10-27 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural contributions of delta class glutathione transferase active-site residues to catalysis Biochem.J., 428, 2010
1PA3	Crystal Structure of Glutathione-S-transferase from Plasmodium falciparum Descriptor: Glutathione s-transferase, putative Authors: Perbandt, M, Betzel, C, Liebau, E. Deposit date: 2003-05-13 Release date: 2003-11-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum J.Biol.Chem., 279, 2004
3CSI	Crystal Structure of the Glutathione Transferase Pi allelic variant*C, I104V/A113V, in complex with the Chlorambucil-Glutathione Conjugate Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CARBONATE ION, ... Authors: Parker, L.J. Deposit date: 2008-04-09 Release date: 2008-07-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J.Mol.Biol., 380, 2008
3F6D	Crystal Structure of a Genetically Modified Delta Class GST (adGSTD4-4) from Anopheles dirus, F123A, in Complex with S-Hexyl Glutathione Descriptor: Glutathione transferase GST1-4, S-HEXYLGLUTATHIONE Authors: Wongsantichon, J, Robinson, R.C, Ketterman, A.J. Deposit date: 2008-11-05 Release date: 2009-10-27 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural contributions of delta class glutathione transferase active-site residues to catalysis Biochem.J., 428, 2010
5AIX	Complex of human hematopoietic prostagandin D2 synthase (hH-PGDS) in complex with an active site inhibitor. Descriptor: 6-(3-methoxyphenyl)-N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]pyridine-3-carboxamide, GLUTATHIONE, HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE, ... Authors: Edfeldt, F, Evenas, J, Lepisto, M, Ward, A, Petersen, J, Wissler, L, Rohman, M, Sivars, U, Svensson, K, Perry, M, Feierberg, I, Zhou, X, Hansson, T, Narjes, F. Deposit date: 2015-02-18 Release date: 2015-06-03 Last modified: 2015-06-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification of Indole Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase (Hh-Pgds). Bioorg.Med.Chem.Lett., 25, 2015
5AIV	Complex of human hematopoietic prostagandin D2 synthase (hH-PGDS) in complex with an active site inhibitor. Descriptor: 3-(1H-indol-4-yl)-N-(3-methoxypropyl)-1,2,4-oxadiazole-5-carboxamide, GLUTATHIONE, HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE, ... Authors: Edfeldt, F, Evenas, J, Lepisto, M, Ward, A, Petersen, J, Wissler, L, Rohman, M, Sivars, U, Svensson, K, Perry, M, Feierberg, I, Zhou, X, Hansson, T, Narjes, F. Deposit date: 2015-02-17 Release date: 2015-06-03 Last modified: 2015-06-10 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Identification of Indole Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase (Hh-Pgds). Bioorg.Med.Chem.Lett., 25, 2015
3CSJ	Human glutathione s-transferase p1-1 in complex with chlorambucil Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORAMBUCIL, CHLORIDE ION, ... Authors: Parker, L.J. Deposit date: 2008-04-09 Release date: 2008-07-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J.Mol.Biol., 380, 2008
1PGT	CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE P1-1[V104] COMPLEXED WITH S-HEXYLGLUTATHIONE Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE Authors: Ji, X. Deposit date: 1997-02-17 Release date: 1997-09-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase. Biochemistry, 36, 1997
1PD2	CRYSTAL STRUCTURE OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE COMPLEX WITH GLUTATHIONE Descriptor: GLUTATHIONE, HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE Authors: Miyano, M, Ago, H. Deposit date: 1998-12-14 Release date: 1999-10-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Cloning and crystal structure of hematopoietic prostaglandin D synthase. Cell(Cambridge,Mass.), 90, 1997
3CRU	Structural characterization of an engineered allosteric protein Descriptor: GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme Authors: Sagermann, M, Chapleau, R, DeLorimier, E, Lei, M. Deposit date: 2008-04-07 Release date: 2009-02-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Using affinity chromatography to engineer and characterize pH-dependent protein switches. Protein Sci., 18, 2009
3CSH	Crystal Structure of Glutathione Transferase Pi in complex with the Chlorambucil-Glutathione Conjugate Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... Authors: Parker, L.J. Deposit date: 2008-04-09 Release date: 2008-07-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.55 Å) Cite: The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J.Mol.Biol., 380, 2008
3CRT	Structural characterization of an engineered allosteric protein Descriptor: GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme Authors: Sagermann, M, Chapleau, R, DeLorimier, E, Lei, M. Deposit date: 2008-04-07 Release date: 2009-02-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Using affinity chromatography to engineer and characterize pH-dependent protein switches. Protein Sci., 18, 2009
1Q4J	Crystal Structure of Pf-GST1 with its inhibitor s-hexyl-GSH Descriptor: Glutathione s-transferase, S-HEXYLGLUTATHIONE Authors: Perbandt, M, Betzel, C, Liebau, E. Deposit date: 2003-08-04 Release date: 2003-11-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum J.Biol.Chem., 279, 2004
3FRC	Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 Descriptor: Glutathione S-transferase, N-[(4S)-4-ammonio-4-carboxybutanoyl]-S-(4-bromobenzyl)-L-cysteinylglycine Authors: Perbandt, M, Liebau, E, Ricci, G. Deposit date: 2009-01-08 Release date: 2010-01-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Tetramerization and Cooperativity in Plasmodium falciparum glutathione transferase are mediated by the atypic loop 113-118 To be Published

<12345678910111213141516>