3EE2

Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole

Summary for 3EE2

Entry DOI	10.2210/pdb3ee2/pdb
Related	1IYH 1IYI 1PD2 1V40 2CVD
Descriptor	Glutathione-requiring prostaglandin D synthase, GLUTATHIONE, nocodazole, ... (5 entities in total)
Functional Keywords	h-pgds, prostanoid production, inflamation, nocodazole, glutathione transferase sigma, fatty acid biosynthesis, isomerase, lipid synthesis, prostaglandin biosynthesis
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : O60760
Total number of polymer chains	2
Total formula weight	47402.66
Authors	Oakley, A.J. (deposition date: 2008-09-04, release date: 2008-09-16, Last modification date: 2023-11-01)
Primary citation	Weber, J.E.,Oakley, A.J.,Christ, A.N.,Clark, A.G.,Hayes, J.D.,Hall, R.,Hume, D.A.,Board, P.G.,Smythe, M.L.,Flanagan, J.U. Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D(2) synthase Eur.J.Med.Chem., 45:447-454, 2010 Cited by PubMed: 19939518 DOI: 10.1016/j.ejmech.2009.10.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation