3EE2
Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutathione-requiring prostaglandin D synthase | polymer | 199 | 23384.9 | 2 | UniProt (O60760) Pfam (PF02798) Pfam (PF14497) | Homo sapiens (Human) | Glutathione-dependent PGD synthetase, Prostaglandin-H2 D-isomerase, Hematopoietic prostaglandin D synthase, H-PGDS |
| 2 | C (A) | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
| 3 | D (A) | nocodazole | non-polymer | 301.3 | 1 | Chemie (NZO) | |||
| 4 | E (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | F, G, H (A, B) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 199 (UniProt: O60760)
| PDB | External Database | Details |
|---|---|---|
| Ile 187 | Val 187 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46769.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 632.9 | |
| All* | Total formula weight | 47402.7 |
