3DD3

Crystal Structure of the Glutathione Transferase Pi enzyme in complex with the bifunctional inhibitor, Etharapta

Summary for 3DD3

Entry DOI	10.2210/pdb3dd3/pdb
Descriptor	Glutathione S-transferase P, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, (eta6-benzene)ruthenium, ... (5 entities in total)
Functional Keywords	transferase, glutathione, detoxification, etharapta, ruthenium, rapta-c, ethacrynic-acid
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	47939.84
Authors	Parker, L.J. (deposition date: 2008-06-05, release date: 2009-04-21, Last modification date: 2023-11-01)
Primary citation	Ang, W.H.,Parker, L.J.,De Luca, A.,Juillerat-Jeanneret, L.,Morton, C.J.,Lo Bello, M.,Parker, M.W.,Dyson, P.J. Rational design of an organometallic glutathione transferase inhibitor Angew.Chem.Int.Ed.Engl., 48:3854-3857, 2009 Cited by PubMed: 19396894 DOI: 10.1002/anie.200900185 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation