6B5B
| Cryo-EM structure of the NAIP5-NLRC4-flagellin inflammasome | 分子名称: | Baculoviral IAP repeat-containing protein 1e, Flagellin, NLR family CARD domain-containing protein 4 | 著者 | Tenthorey, J.L, Haloupek, N, Lopez-Blanco, J.R, Grob, P, Adamson, E, Hartenian, E, Lind, N.A, Bourgeois, N.M, Chacon, P, Nogales, E, Vance, R.E. | 登録日 | 2017-09-29 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion. Science, 358, 2017
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6BZE
| Cryo-EM structure of BCL10 CARD filament | 分子名称: | B-cell lymphoma/leukemia 10 | 著者 | David, L, Li, Y, Ma, J, Garner, E, Zhang, X, Wu, H. | 登録日 | 2017-12-23 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E25
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6E26
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6E27
| The CARD9 CARD domain-swapped dimer with a zinc ion bound to one of the two zinc binding sites | 分子名称: | Caspase recruitment domain-containing protein 9, ZINC ION | 著者 | Holliday, M.J, Ferrao, R, Boenig, G, Deuber, E.C, Fairbrother, W.J. | 登録日 | 2018-07-10 | 公開日 | 2018-09-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | 主引用文献 | Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. J. Biol. Chem., 293, 2018
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6E28
| The CARD9 CARD domain-swapped dimer | 分子名称: | Caspase recruitment domain-containing protein 9 | 著者 | Holliday, M.J, Ferrao, R, Boenig, G, Deuber, E.C, Fairbrother, W.J. | 登録日 | 2018-07-10 | 公開日 | 2018-09-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. J. Biol. Chem., 293, 2018
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6GFJ
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6GGS
| Structure of RIP2 CARD filament | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2 | 著者 | Pellegrini, E, Cusack, S, Desfosses, A, Schoehn, G, Malet, H, Gutsche, I, Sachse, C, Hons, M. | 登録日 | 2018-05-03 | 公開日 | 2018-10-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling. Nat Commun, 9, 2018
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6GJZ
| CryoEM structure of the MDA5-dsRNA filament in complex with AMPPNP | 分子名称: | Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ... | 著者 | Yu, Q, Qu, K, Modis, Y. | 登録日 | 2018-05-17 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | 主引用文献 | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
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6GK2
| Helical reconstruction of BCL10 CARD and MALT1 DEATH DOMAIN complex | 分子名称: | B-cell lymphoma/leukemia 10, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 著者 | Schlauderer, F, Desfosses, A, Gutsche, I, Hopfner, K.P, Lammens, K. | 登録日 | 2018-05-18 | 公開日 | 2018-10-31 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Molecular architecture and regulation of BCL10-MALT1 filaments. Nat Commun, 9, 2018
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6GKH
| CryoEM structure of the MDA5-dsRNA filament in complex with ADP-AlF4 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ... | 著者 | Yu, Q, Qu, K, Modis, Y. | 登録日 | 2018-05-21 | 公開日 | 2018-11-21 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | 主引用文献 | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
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6GKM
| CryoEM structure of the MDA5-dsRNA filament in complex with ATP (10 mM) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), ... | 著者 | Yu, Q, Qu, K, Modis, Y. | 登録日 | 2018-05-21 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
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6GWM
| Solution structure of rat RIP2 caspase recruitment domain | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2 | 著者 | Mineev, K.S, Goncharuk, S.A, Artemieva, L.E, Arseniev, A.S. | 登録日 | 2018-06-25 | 公開日 | 2018-10-31 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | CARD domain of rat RIP2 kinase: Refolding, solution structure, pH-dependent behavior and protein-protein interactions. PLoS ONE, 13, 2018
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6H61
| CryoEM structure of the MDA5-dsRNA filament with 89 degree twist and without nucleotide | 分子名称: | Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ... | 著者 | Yu, Q, Qu, K, Modis, Y. | 登録日 | 2018-07-25 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | 主引用文献 | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
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6H66
| CryoEM structure of the MDA5-dsRNA filament with 93 degree twist and without nucleotide | 分子名称: | Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ... | 著者 | Yu, Q, Qu, K, Modis, Y. | 登録日 | 2018-07-26 | 公開日 | 2018-11-21 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
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6J52
| Crystal structure of CARD-only protein in frog virus 3 | 分子名称: | Caspase recruitment domain-only protein | 著者 | Park, H.H, Kwon, S. | 登録日 | 2019-01-10 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.504 Å) | 主引用文献 | Structural transformation-mediated dimerization of caspase recruitment domain revealed by the crystal structure of CARD-only protein in frog virus 3. J. Struct. Biol., 205, 2019
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6K7V
| Structure of NLRP1 CARD filament | 分子名称: | NACHT, LRR and PYD domains-containing protein 1 | 著者 | Gong, Q, Xu, C, Zhang, J, Wu, B. | 登録日 | 2019-06-09 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nat Commun, 12, 2021
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6K8J
| Structure of NLRC4 CARD filament | 分子名称: | NLR family CARD domain-containing protein 4 | 著者 | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | 登録日 | 2019-06-12 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nat Commun, 12, 2021
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6K99
| Structure of ASC CARD filament | 分子名称: | Apoptosis-associated speck-like protein containing a CARD | 著者 | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | 登録日 | 2019-06-14 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nat Commun, 12, 2021
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6K9F
| Structure of unknow protein 4 | 分子名称: | Caspase recruitment domain-containing protein 8 | 著者 | Gong, Q, Xu, C, Zhang, J, Boo, Z.Z, Wu, B. | 登録日 | 2019-06-15 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nat Commun, 12, 2021
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6KI0
| Crystal Structure of Human ASC-CARD | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Xu, Z.H, Jin, T.C. | 登録日 | 2019-07-16 | 公開日 | 2020-07-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome. Cell Death Dis, 12, 2021
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6MKS
| Cryo-EM structure of NLRC4-CARD filament | 分子名称: | Chimera protein of NLR family CARD domain-containing protein 4 and EGFP | 著者 | Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H. | 登録日 | 2018-09-26 | 公開日 | 2018-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly. J. Biol. Chem., 293, 2018
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6N1H
| Cryo-EM structure of ASC-CARD filament | 分子名称: | Apoptosis-associated speck-like protein containing a CARD | 著者 | Li, Y, Fu, T, Wu, H. | 登録日 | 2018-11-08 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6N1I
| Cryo-EM structure of NLRC4-CARD filament | 分子名称: | NLR family CARD domain-containing protein 4 | 著者 | Li, Y, Fu, T, Wu, H. | 登録日 | 2018-11-08 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6N2M
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