8SAY
| CryoEM structure of DH270.3-CH848.10.17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
|
|
8SB2
| CryoEM structure of DH270.I2-CH848.10.17 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
|
|
8SB3
| CryoEM structure of DH270.2-CH848.10.17 | Descriptor: | CH848.10.17 gp120, CH848.10.17.SOSIP gp41, DH270.2 Variable Heavy chain, ... | Authors: | Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. | Deposit date: | 2023-04-02 | Release date: | 2023-04-19 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
|
|
7TXD
| Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing darpin bnd.9, ... | Authors: | Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. | Deposit date: | 2022-02-08 | Release date: | 2023-04-12 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nat.Struct.Mol.Biol., 30, 2023
|
|
8FIS
| Structure of Bispecific CAP256V2LS-J3 Fab in complex with BG505 DS-SOSIP.664 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Gorman, J, Kwong, P.D. | Deposit date: | 2022-12-16 | Release date: | 2023-02-01 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency. Mabs, 15, 2023
|
|
8EU8
| Cryo-EM structure of CH848 10.17DT DS-SOSIP-2P Env | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 10.17DT SOSIP Envelope glycoprotein gp160 | Authors: | Wrapp, D, Acharya, P, Haynes, B.F. | Deposit date: | 2022-10-18 | Release date: | 2023-01-04 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Structure-Based Stabilization of SOSIP Env Enhances Recombinant Ectodomain Durability and Yield. J.Virol., 97, 2023
|
|
8DVD
| |
8D5C
| anti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4 | Descriptor: | CG10 Fab heavy chain, CG10 Fab light chain, Envelope glycoprotein gp160, ... | Authors: | Yang, Z, Bjorkman, P.J, Gershoni, J.M. | Deposit date: | 2022-06-04 | Release date: | 2022-11-16 | Last modified: | 2023-01-04 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers. J.Virol., 96, 2022
|
|
7SD3
| Cytoplasmic tail deleted HIV-1 Env bound with three 4E10 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4E10 Fab heavy chain, ... | Authors: | Yang, S, Walz, T. | Deposit date: | 2021-09-29 | Release date: | 2022-11-09 | Last modified: | 2023-02-22 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack. Nat Commun, 13, 2022
|
|
7SC5
| Cytoplasmic tail deleted HIV Env trimer in nanodisc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Yang, S, Walz, T. | Deposit date: | 2021-09-27 | Release date: | 2022-11-09 | Last modified: | 2023-02-22 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack. Nat Commun, 13, 2022
|
|
7UGP
| |
7UGO
| |
7UGN
| |
8DUA
| SIV E660.CR54 SOS-2P Env Trimer with ITS92.02 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ... | Authors: | Gorman, J, Kwong, P.D. | Deposit date: | 2022-07-27 | Release date: | 2022-10-26 | Last modified: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (4.32 Å) | Cite: | Cryo-EM structures of prefusion SIV envelope trimer. Nat.Struct.Mol.Biol., 29, 2022
|
|
7T4G
| |
7T2P
| |
7T9A
| ApexGT2 in complex with GT2-d42.16 and RM20A3 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GT2-d42.16 Fab Heavy Chain, ... | Authors: | Berndsen, Z.T, Ward, A.B. | Deposit date: | 2021-12-18 | Release date: | 2022-09-28 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
|
|
7T9B
| ApexGT5 in complex with GT5-d42.16 and RM20A3 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Berndsen, Z.T, Ward, A.B. | Deposit date: | 2021-12-18 | Release date: | 2022-09-28 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens Immunity, 2022
|
|
7UCF
| |
7UCG
| |
7SQ1
| BG505.MD39TS Env trimer in complex with Fab from antibody C05 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 Fab Light chain, ... | Authors: | Moore, A, Du, J, Xu, Z, Walker, S, Kulp, D.W, Pallesen, J. | Deposit date: | 2021-11-04 | Release date: | 2022-06-22 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer. Nat Commun, 13, 2022
|
|
7N28
| |
7MXD
| |
7SKA
| Sub-tomogram averaged structure of HIV-1 Envelope protein in native membrane | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(2-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Mangala Prasad, V, Lee, K.K. | Deposit date: | 2021-10-20 | Release date: | 2022-03-09 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice. Cell, 185, 2022
|
|
7LXN
| Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env glycoprotein gp120, ... | Authors: | Martin, G.M, Ward, A.B, Sattentau, Q.J. | Deposit date: | 2021-03-04 | Release date: | 2022-03-09 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Npj Vaccines, 8, 2023
|
|