7SD3

Cytoplasmic tail deleted HIV-1 Env bound with three 4E10 Fabs

Summary for 7SD3

• Entry DOI: 10.2210/pdb7sd3/pdb
• EMDB information: 25022 25024 25025 25045
• Descriptor: 4E10 Fab light chain, 4E10 Fab heavy chain, Envelope glycoprotein gp120, ... (7 entities in total)
• Functional Keywords: hiv, envelope, spike, fab, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 12
• Total formula weight: 376769.32

Authors

Yang, S.,Walz, T. (deposition date: 2021-09-29, release date: 2022-11-09, Last modification date: 2023-02-22)

• Primary citation: Yang, S.,Hiotis, G.,Wang, Y.,Chen, J.,Wang, J.H.,Kim, M.,Reinherz, E.L.,Walz, T.; Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack.; Nat Commun, 13:6393-6393, 2022; PubMed: 36302771; DOI: 10.1038/s41467-022-34008-y

Experimental method

ELECTRON MICROSCOPY (3.67 Å)