7T9A

ApexGT2 in complex with GT2-d42.16 and RM20A3 Fabs

This is a non-PDB format compatible entry.

Summary for 7T9A

• Entry DOI: 10.2210/pdb7t9a/pdb
• EMDB information: 25754
• Descriptor: HIV Envelope ApexGT2 gp120, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: hiv, germline targeting, vaccine, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 14
• Total formula weight: 341446.98

Authors

Berndsen, Z.T.,Ward, A.B. (deposition date: 2021-12-18, release date: 2022-09-28, Last modification date: 2023-07-05)

• Primary citation: Melzi, E.,Willis, J.,Ma, K.,Lin, Y.,Kratochvil, S.,Berndsen, Z.T.,Nair, U.,Warner, J.,Steichen, J.,Pecetta, S.,Perez, M.,Kirsch, K.,Ward, A.B.,Schief, W.,Batista, F.D.; Priming HIV Envelope V2 Apex-directed broadly neutralizing antibody responses with protein or mRNA immunogens; Immunity, 2022

Experimental method

ELECTRON MICROSCOPY (3.54 Å)