7SQ1

BG505.MD39TS Env trimer in complex with Fab from antibody C05

Summary for 7SQ1

• Entry DOI: 10.2210/pdb7sq1/pdb
• EMDB information: 25376
• Descriptor: Transmembrane protein gp41, Envelope glycoprotein gp160, C05 Fab Light chain, ... (9 entities in total)
• Functional Keywords: antibody, env, envelope, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 10
• Total formula weight: 282506.51

Authors

Moore, A.,Du, J.,Xu, Z.,Walker, S.,Kulp, D.W.,Pallesen, J. (deposition date: 2021-11-04, release date: 2022-06-22, Last modification date: 2022-12-07)

• Primary citation: Xu, Z.,Walker, S.,Wise, M.C.,Chokkalingam, N.,Purwar, M.,Moore, A.,Tello-Ruiz, E.,Wu, Y.,Majumdar, S.,Konrath, K.M.,Kulkarni, A.,Tursi, N.J.,Zaidi, F.I.,Reuschel, E.L.,Patel, I.,Obeirne, A.,Du, J.,Schultheis, K.,Gites, L.,Smith, T.,Mendoza, J.,Broderick, K.E.,Humeau, L.,Pallesen, J.,Weiner, D.B.,Kulp, D.W.; Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.; Nat Commun, 13:695-695, 2022; PubMed: 35121758; DOI: 10.1038/s41467-022-28363-z

Experimental method

ELECTRON MICROSCOPY (3.8 Å)