7SQ1
BG505.MD39TS Env trimer in complex with Fab from antibody C05
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, G (B, D, F) | Transmembrane protein gp41 | polymer | 153 | 17134.3 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 | TM, Glycoprotein 41, gp41 |
| 2 | B, D, H (C, E, G) | Envelope glycoprotein gp160 | polymer | 472 | 52917.9 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 | Env polyprotein |
| 3 | E, I (L, I) | C05 Fab Light chain | polymer | 111 | 12031.5 | 2 | Mus musculus | ||
| 4 | F, J (H, A) | C05 Fab heavy chain | polymer | 122 | 13727.2 | 2 | Mus musculus | ||
| 5 | AA, BA, CA, DA, EA... (a, b, c, d, e...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 21 | In PDB GlyTouCan (G42666HT) | |||
| 6 | O (O) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose | branched | 342.3 | 1 | In PDB GlyTouCan (G07696MJ) | |||
| 7 | FA, GA, U (f, g, U) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 8 | V (V) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 9 | AB, BB, CB, DB, EB... (D, E, B, F, C...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 41 | Chemie (NAG) |
Sequence modifications
B, D, F: 512 - 664 (UniProt: Q2N0S6)
C, E, G: 32 - 505 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Ser 519 | Phe 516 | conflict |
| Pro 559 | Ile 556 | conflict |
| Pro 561 | Ala 558 | conflict |
| Asp 568 | Leu 565 | conflict |
| His 570 | Val 567 | conflict |
| His 585 | Arg 582 | conflict |
| Cys 605 | Thr 602 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 106 | Thr 105 | conflict |
| Ile 271 | Met 270 | conflict |
| Leu 288 | Phe 287 | conflict |
| Val 304 | Arg 303 | conflict |
| Tyr 319 | Ala 316 | conflict |
| Asn 332 | Thr 330 | conflict |
| Gln 363 | Asn 361 | conflict |
| Cys 501 | Ala 498 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 261674.0 | |
| Branched | Number of molecules | 26 |
| Total formula weight | 11763.0 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 9069.5 | |
| All* | Total formula weight | 282506.5 |
