2A74
 
 | | Human Complement Component C3c | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Complement Component C3c, GLYCEROL, ... | | 著者 | Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P. | | 登録日 | 2005-07-04 | | 公開日 | 2005-09-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
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2A73
 | | Human Complement Component C3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P. | | 登録日 | 2005-07-04 | | 公開日 | 2005-09-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
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2I07
 | | Human Complement Component C3b | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3b, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Janssen, B.J.C, Christodoulidou, A, McCarthy, A, Lambris, J.D, Gros, P. | | 登録日 | 2006-08-10 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
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2ICE
 | | CRIg bound to C3c | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ... | | 著者 | Wiesmann, C. | | 登録日 | 2006-09-12 | | 公開日 | 2006-11-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
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2ICF
 | | CRIg bound to C3b | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ... | | 著者 | Wiesmann, C. | | 登録日 | 2006-09-12 | | 公開日 | 2006-11-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
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2PN5
 | | Crystal Structure of TEP1r | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | | 著者 | Baxter, R.H.G. | | 登録日 | 2007-04-23 | | 公開日 | 2007-07-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | | 主引用文献 | Structural basis for conserved complement factor-like function in the antimalarial protein TEP1
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QKI
 | | Human C3c in complex with the inhibitor compstatin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Complement C3, ... | | 著者 | Janssen, B.J.C, Halff, E.F, Lambris, J.D, Gros, P. | | 登録日 | 2007-07-11 | | 公開日 | 2007-08-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
J.Biol.Chem., 282, 2007
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3CU7
 | | Human Complement Component 5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | | 著者 | Fredslund, F, Andersen, G.R. | | 登録日 | 2008-04-16 | | 公開日 | 2008-06-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.105 Å) | | 主引用文献 | Structure of and influence of a tick complement inhibitor on human complement component 5
Nat.Immunol., 9, 2008
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3FRP
 | | Crystal Structure of Cobra Venom Factor, a Co-factor for C3- and C5 convertase CVFBb | | 分子名称: | CALCIUM ION, Cobra venom factor alpha chain, Cobra venom factor beta chain, ... | | 著者 | Krishnan, V, Narayana, S.V.L. | | 登録日 | 2009-01-08 | | 公開日 | 2009-04-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb.
Structure, 17, 2009
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3G6J
 | | C3b in complex with a C3b specific Fab | | 分子名称: | CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ... | | 著者 | Wiesmann, C. | | 登録日 | 2009-02-06 | | 公開日 | 2009-03-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement
J.Biol.Chem., 284, 2009
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2WII
 | | Complement C3b in complex with factor H domains 1-4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ... | | 著者 | Wu, J, Janssen, B.J.C, Gros, P. | | 登録日 | 2009-05-12 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat. Immunol., 10, 2009
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2WIN
 | | C3 convertase (C3bBb) stabilized by SCIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, ... | | 著者 | Wu, J, Janssen, B.J, Gros, P. | | 登録日 | 2009-05-13 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Nat. Immunol., 10, 2009
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3HRZ
 | | Cobra Venom Factor (CVF) in complex with human factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | | 登録日 | 2009-06-10 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Embo J., 28, 2009
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3HS0
 | | Cobra Venom Factor (CVF) in complex with human factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | | 登録日 | 2009-06-10 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Embo J., 28, 2009
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3KLS
 | | Structure of complement C5 in complex with SSL7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | | 著者 | Laursen, N.S, Gordon, N, Hermans, S, Lorenz, N, Jackson, N, Wines, B, Spillner, E, Christensen, J.B, Jensen, M, Fredslund, F, Bjerre, M, Sottrup-Jensen, L, Fraser, J.D, Andersen, G.R. | | 登録日 | 2009-11-09 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus
Proc.Natl.Acad.Sci.USA, 107, 2010
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3KM9
 | | Structure of complement C5 in complex with the C-terminal beta-grasp domain of SSL7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | | 著者 | Laursen, N.S, Gordon, N, Hermans, S, Lorenz, N, Jackson, N, Wines, B, Spillner, E, Christensen, J.B, Jensen, M, Fredslund, F, Bjerre, M, Sottrup-Jensen, L, Fraser, J.D, Andersen, G.R. | | 登録日 | 2009-11-10 | | 公開日 | 2009-12-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus
Proc.Natl.Acad.Sci.USA, 107, 2010
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3L3O
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3L5N
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3NMS
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3OHX
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2XWB
 | | Crystal Structure of Complement C3b in complex with Factors B and D | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ... | | 著者 | Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. | | 登録日 | 2010-11-01 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
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2XWJ
 | | Crystal Structure of Complement C3b in Complex with Factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ... | | 著者 | Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. | | 登録日 | 2010-11-04 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
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3PRX
 | | Structure of Complement C5 in Complex with CVF and SSL7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | | 著者 | Laursen, N.S, Andersen, G.R, Sottrup-Jensen, L, Andersen, K.R, Spillner, E, Braren, I. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
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3PVM
 | | Structure of Complement C5 in Complex with CVF | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, Complement C5 | | 著者 | Laursen, N.S, Andersen, K.R, Braren, I, Sottrup-Jensen, L, Spillner, E, Andersen, G.R. | | 登録日 | 2010-12-07 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
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3T4A
 | | Structure of a truncated form of Staphylococcal Complement Inhibitor B bound to human C3c at 3.4 Angstrom resolution | | 分子名称: | Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ... | | 著者 | Garcia, B.L, Geisbrecht, B.V, Summers, B.J. | | 登録日 | 2011-07-25 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family.
J.Biol.Chem., 287, 2012
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