2QKI
Human C3c in complex with the inhibitor compstatin
Summary for 2QKI
Entry DOI | 10.2210/pdb2qki/pdb |
Related | 1A1P 2A73 2A74 2I07 2ICE 2ICF |
Descriptor | Complement C3, compstatin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | immunity, complement inhibitor design, c3, compstatin, immune system-hydrolase inhibitor complex, immune system/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01024 P01024 P01024 |
Total number of polymer chains | 8 |
Total formula weight | 273113.36 |
Authors | Janssen, B.J.C.,Halff, E.F.,Lambris, J.D.,Gros, P. (deposition date: 2007-07-11, release date: 2007-08-14, Last modification date: 2023-08-30) |
Primary citation | Janssen, B.J.,Halff, E.F.,Lambris, J.D.,Gros, P. Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition. J.Biol.Chem., 282:29241-29247, 2007 Cited by PubMed: 17684013DOI: 10.1074/jbc.M704587200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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