2QKI
Human C3c in complex with the inhibitor compstatin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Complement C3 | polymer | 643 | 71267.2 | 2 | UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) In PDB | Homo sapiens (human) | |
| 2 | B, E | Complement C3 | polymer | 188 | 21521.8 | 2 | UniProt (P01024) Pfam (PF00207) In PDB | Homo sapiens (human) | |
| 3 | C, F | Complement C3 | polymer | 343 | 39537.4 | 2 | UniProt (P01024) Pfam (PF21308) Pfam (PF07677) Pfam (PF01759) In PDB | Homo sapiens (human) | |
| 4 | G, H | compstatin | polymer | 15 | 1600.8 | 2 | |||
| 5 | I, J | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | C, D, F, A | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) | |||
| 7 | B, C, E, D, F... | BROMIDE ION | non-polymer | 79.9 | 32 | Chemie (BR) | |||
| 8 | D, B, C, E, F... | GLYCEROL | non-polymer | 92.1 | 18 | Chemie (GOL) | |||
| 9 | water | water | 18.0 | 471 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 643 (UniProt: P01024)
| PDB | External Database | Details |
|---|---|---|
| Leu 292 | Pro 292 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 267854.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 55 |
| Total formula weight | 4410.1 | |
| All* | Total formula weight | 273113.4 |
