3KM9
Structure of complement C5 in complex with the C-terminal beta-grasp domain of SSL7
Summary for 3KM9
Entry DOI | 10.2210/pdb3km9/pdb |
Related | 2QEJ 3CU7 3KLS |
Descriptor | Complement C5, Staphylococcal enterotoxin-like toxin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | ob-fold, beta-grasp domain, fn3 domain, cleavage on pair of basic residues, complement alternate pathway, complement pathway, cytolysis, disulfide bond, glycoprotein, immune response, inflammatory response, innate immunity, membrane attack complex, secreted, immune system |
Biological source | Staphylococcus aureus subsp. aureus More |
Total number of polymer chains | 4 |
Total formula weight | 402446.22 |
Authors | Laursen, N.S.,Gordon, N.,Hermans, S.,Lorenz, N.,Jackson, N.,Wines, B.,Spillner, E.,Christensen, J.B.,Jensen, M.,Fredslund, F.,Bjerre, M.,Sottrup-Jensen, L.,Fraser, J.D.,Andersen, G.R. (deposition date: 2009-11-10, release date: 2009-12-01, Last modification date: 2023-11-01) |
Primary citation | Laursen, N.S.,Gordon, N.,Hermans, S.,Lorenz, N.,Jackson, N.,Wines, B.,Spillner, E.,Christensen, J.B.,Jensen, M.,Fredslund, F.,Bjerre, M.,Sottrup-Jensen, L.,Fraser, J.D.,Andersen, G.R. Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus Proc.Natl.Acad.Sci.USA, 107:3681-3686, 2010 Cited by PubMed: 20133685DOI: 10.1073/pnas.0910565107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.2 Å) |
Structure validation
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