3CU7

Human Complement Component 5

Summary for 3CU7

Entry DOI	10.2210/pdb3cu7/pdb
Descriptor	Complement C5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	mg domain, complement, inflammation, anaphylatoxin, cleavage on pair of basic residues, complement alternate pathway, complement pathway, cytolysis, glycoprotein, immune response, inflammatory response, innate immunity, membrane attack complex, secreted, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	379355.17
Authors	Fredslund, F.,Andersen, G.R. (deposition date: 2008-04-16, release date: 2008-06-10, Last modification date: 2023-11-01)
Primary citation	Fredslund, F.,Laursen, N.S.,Roversi, P.,Jenner, L.,Oliveira, C.L.P.,Pedersen, J.S.,Nunn, M.A.,Lea, S.M.,Discipio, R.,Sottrup-Jensen, L.,Andersen, G.R. Structure of and influence of a tick complement inhibitor on human complement component 5 Nat.Immunol., 9:753-760, 2008 Cited by PubMed: 18536718 DOI: 10.1038/ni.1625 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.105 Å)

Structure validation