2ICF
CRIg bound to C3b
Summary for 2ICF
Entry DOI | 10.2210/pdb2icf/pdb |
Related | 2A73 2A74 2ICC 2ICE |
Descriptor | Complement C3 beta chain, Complement C3 alpha chain, V-set and immunoglobulin domain-containing protein 4, ... (6 entities in total) |
Functional Keywords | alternate pathway, complement, c3, c3b, crig, complement receptor, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01024 P01024 Membrane; Single-pass type I membrane protein (Probable): Q9Y279 |
Total number of polymer chains | 3 |
Total formula weight | 189754.39 |
Authors | Wiesmann, C. (deposition date: 2006-09-12, release date: 2006-11-07, Last modification date: 2020-07-29) |
Primary citation | Wiesmann, C.,Katschke, K.J.,Yin, J.,Helmy, K.Y.,Steffek, M.,Fairbrother, W.J.,McCallum, S.A.,Embuscado, L.,DeForge, L.,Hass, P.E.,van Lookeren Campagne, M. Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature, 444:217-220, 2006 Cited by PubMed: 17051150DOI: 10.1038/nature05263 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.1 Å) |
Structure validation
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