2A73

Human Complement Component C3

Summary for 2A73

DescriptorComplement C3, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ... (5 entities in total)
Functional Keywordsintact thioester, immune system
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01024 P01024
Total number of polymer chains2
Total molecular weight185775.3
Authors
Janssen, B.J.C.,Huizinga, E.G.,Raaijmakers, H.C.A.,Roos, A.,Daha, M.R.,Nilsson-Ekdahl, K.,Nilsson, B.,Gros, P. (deposition date: 2005-07-04, release date: 2005-09-27, Last modification date: 2011-07-13)
Primary citation
Janssen, B.J.,Huizinga, E.G.,Raaijmakers, H.C.,Roos, A.,Daha, M.R.,Nilsson-Ekdahl, K.,Nilsson, B.,Gros, P.
Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437:505-511, 2005
PubMed: 16177781 (PDB entries with the same primary citation)
DOI: 10.1038/nature04005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.287112.6%9.5%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report