Human Complement Component C3

Summary for 2A73

DescriptorComplement C3, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ... (5 entities in total)
Functional Keywordsintact thioester, immune system
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01024 P01024
Total number of polymer chains2
Total molecular weight185775.3
Janssen, B.J.C.,Huizinga, E.G.,Raaijmakers, H.C.A.,Roos, A.,Daha, M.R.,Nilsson-Ekdahl, K.,Nilsson, B.,Gros, P. (deposition date: 2005-07-04, release date: 2005-09-27, Last modification date: 2011-07-13)
Primary citation
Janssen, B.J.,Huizinga, E.G.,Raaijmakers, H.C.,Roos, A.,Daha, M.R.,Nilsson-Ekdahl, K.,Nilsson, B.,Gros, P.
Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437:505-511, 2005
PubMed: 16177781 (PDB entries with the same primary citation)
DOI: 10.1038/nature04005
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.287112.6%9.5%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report