Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004866 | molecular_function | endopeptidase inhibitor activity |
| B | 0004866 | molecular_function | endopeptidase inhibitor activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006954 | biological_process | inflammatory response |
| B | 0006956 | biological_process | complement activation |
Functional Information from PROSITE/UniProt
| site_id | PS00477 |
| Number of Residues | 9 |
| Details | ALPHA_2_MACROGLOBULIN Alpha-2-macroglobulin family thiolester region signature. PsGCGEQnM |
| Chain | Residue | Details |
| B | PRO985-MET993 | |
| site_id | PS01177 |
| Number of Residues | 36 |
| Details | ANAPHYLATOXIN_1 Anaphylatoxin domain signature. CCedGmrenpmrfSCQrrtrfisl.GeaCkkvfld.CC |
| Chain | Residue | Details |
| B | CYS671-CYS706 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by carboxypeptidases |
| Chain | Residue | Details |
| B | ALA725 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by C3 convertase |
| Chain | Residue | Details |
| B | ARG726 | |
| A | SER48 | |
| A | SER275 | |
| A | SER281 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by factor I => ECO:0000255 |
| Chain | Residue | Details |
| B | ARG932 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by factor I |
| Chain | Residue | Details |
| B | ARG1281 | |
| B | ARG1298 | |
| Chain | Residue | Details |
| B | ASN1641 | |
| Chain | Residue | Details |
| B | SER946 | |
| B | SER1299 | |
| B | SER1551 | |
| Chain | Residue | Details |
| B | ASN917 | |
| Chain | Residue | Details |
| B | ASN1595 | |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CROSSLNK: Isoglutamyl cysteine thioester (Cys-Gln) |
| Chain | Residue | Details |
| B | CYS988 | |
| B | GLN991 | |
