PDB: 90 件ウェブページステータス検索Chemie searchBIRD

---

7ZR6	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-28 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7ZUB	Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex 分子名称: (3~{Z})-3-(3-oxidanylidene-1~{H}-indol-2-ylidene)-1~{H}-indol-2-one, ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, ... 著者 Gruszczyk, J, Savva, C.G, Lai-Kee-Him, J, Bous, J, Ancelin, A, Kwong, H.S, Grandvuillemin, L, Bourguet, W. 登録日 2022-05-12 公開日 2022-11-23 最終更新日 2022-12-07 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex. Nat Commun, 13, 2022
8EOA	Cryo-EM structure of human HSP90B-AIPL1 complex 分子名称: Aryl-hydrocarbon-interacting protein-like 1, Heat shock protein HSP 90-beta, MAGNESIUM ION, ... 著者 Srivastava, D, Artemyev, N.O. 登録日 2022-10-02 公開日 2023-01-25 最終更新日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1. Structure, 31, 2023
8EOB	Cryo-EM structure of human HSP90B in the closed state 分子名称: Heat shock protein HSP 90-beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Srivastava, D, Artemyev, N.O. 登録日 2022-10-02 公開日 2023-01-25 最終更新日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1. Structure, 31, 2023
8FFV	Cryo-EM structure of the GR-Hsp90-FKBP52 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Agard, D.A. 登録日 2022-12-10 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8FFW	Cryo-EM structure of the GR-Hsp90-FKBP51 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... 著者 Noddings, C.M, Agard, D.A. 登録日 2022-12-10 公開日 2023-11-01 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor. Nat.Struct.Mol.Biol., 30, 2023
8FX4	GC-C-Hsp90-Cdc37 regulatory complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Guanylyl cyclase C, Heat shock protein HSP 90-beta, ... 著者 Caveney, N.A, Garcia, K.C. 登録日 2023-01-23 公開日 2023-07-12 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural insight into guanylyl cyclase receptor hijacking of the kinase-Hsp90 regulatory mechanism. Elife, 12, 2023
8GAE	Hsp90 provides platform for CRaf dephosphorylation by PP5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... 著者 Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. 登録日 2023-02-22 公開日 2023-04-26 最終更新日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
8GFT	Hsp90 provides platform for CRaf dephosphorylation by PP5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... 著者 Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. 登録日 2023-03-08 公開日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
8H77	Hsp90-AhR-p23-XAP2 complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... 著者 Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. 登録日 2022-10-19 公開日 2023-01-04 最終更新日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of the cytosolic AhR complex. Structure, 31, 2023
8OXU	Crystal Structure of the Hsp90-LA1011 Complex 分子名称: ATP-dependent molecular chaperone HSP82, dimethyl 2,6-bis[2-(dimethylamino)ethyl]-1-methyl-4-[4-(trifluoromethyl)phenyl]-4~{H}-pyridine-3,5-dicarboxylate 著者 Roe, S.M, Prodromou, C. 登録日 2023-05-02 公開日 2023-07-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 The Crystal Structure of the Hsp90-LA1011 Complex and the Mechanism by Which LA1011 May Improve the Prognosis of Alzheimer's Disease. Biomolecules, 13, 2023
8QMO	Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... 著者 Kwong, H.S, Grandvuillemin, L, Sirounian, S, Ancelin, A, Lai-Kee-Him, J, Carivenc, C, Lancey, C, Ragan, T.J, Hesketh, E.L, Bourguet, W, Gruszczyk, J. 登録日 2023-09-24 公開日 2024-01-10 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds. J.Mol.Biol., 436, 2024
8U1L	Cryo-EM structure of the RAF1-HSP90-CDC37 complex in the closed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, Hsp90 co-chaperone Cdc37, ... 著者 Finci, L.I, Simanshu, D.K. 登録日 2023-09-01 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements. Commun Biol, 7, 2024
8U1M	Cryo-EM structure of the HSP90 dimer (NTD-MD) in the semi-open state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, MAGNESIUM ION 著者 Finci, L.I, Simanshu, D.K. 登録日 2023-09-01 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements. Commun Biol, 7, 2024
8U1N	Cryo-EM structure of the cross-linked HSP90 dimer (NTD-MD) in the semi-open state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 83, MAGNESIUM ION 著者 Finci, L.I, Simanshu, D.K. 登録日 2023-09-01 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements. Commun Biol, 7, 2024

<1234