PDB: 255 件ウェブページステータス検索Chemie searchBIRD

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4IC0	Crystal Structure of PAI-1 in Complex with Gallate 分子名称: 3,4,5-trihydroxybenzoic acid, Plasminogen activator inhibitor 1 著者 Hong, Z.B, Lin, Z.H, Gong, L.H, Huang, M.D. 登録日 2012-12-09 公開日 2013-12-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Crystal Structure of PAI-1 in Complex with Gallate To be Published
4BB2	Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone 分子名称: 1,2-ETHANEDIOL, CORTICOSTEROID-BINDING GLOBULIN, CYSTEINE, ... 著者 Gardill, B.R, Vogl, M.R, Lin, H, Hammond, G.L, Muller, Y.A. 登録日 2012-09-19 公開日 2012-12-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences Plos One, 7, 2012
4GA7	Crystal structure of human serpinB1 mutant 分子名称: Leukocyte elastase inhibitor 著者 Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. 登録日 2012-07-25 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
4G8R	Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 分子名称: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION 著者 Stuckey, J.A, Lawrence, D.A, Li, S.-H. 登録日 2012-07-23 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
4G8O	Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 分子名称: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), 1,2-ETHANEDIOL, Plasminogen activator inhibitor 1, ... 著者 Stuckey, J.A, Lawrence, D.A, Li, S.-H. 登録日 2012-07-23 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
4AU4	Crystal Structure of Hsp47 分子名称: SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, ... 著者 Widmer, C, Gebauer, J.M, Brunstein, E, Rodenbaum, S, Zaucke, F, Drogemuller, C, Leeb, T, Baumann, U. 登録日 2012-05-14 公開日 2012-08-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
4AU2	Crystal Structure of a Hsp47-collagen complex 分子名称: 15ER COLLAGEN MODEL PEPTIDE 15-R8, SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), ... 著者 Widmer, C, Gebauer, J.M, Brunstein, E, Drogemuller, C, Leeb, T, Baumann, U. 登録日 2012-05-13 公開日 2012-08-15 最終更新日 2015-04-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
4AQH	Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR 1, TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE 著者 Fjellstrom, O, Deinum, J, Sjogren, T, Johansson, C, Geschwindner, S, Nerme, V, Legnehed, A, McPheat, J, Olsson, K, Bodin, C, Gustafsson, D. 登録日 2012-04-17 公開日 2012-11-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation J.Biol.Chem., 288, 2013
4EB1	Hyperstable in-frame insertion variant of antithrombin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III 著者 Martinez-Martinez, I, Johnson, D.J.D, Yamasaki, M, Corral, J, Huntington, J.A. 登録日 2012-03-23 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevance. J.Thromb.Haemost., 10, 2012
4DY0	Crystal structure of native protease nexin-1 with heparin 分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, GLYCEROL, Glia-derived nexin, ... 著者 Huntington, J.A, Li, W. 登録日 2012-02-28 公開日 2012-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism. Blood, 120, 2012
4DY7	Crystal structures of protease nexin-1 in complex with S195A thrombin 分子名称: ACETATE ION, CALCIUM ION, Glia-derived nexin, ... 著者 Huntington, J.A, Li, W. 登録日 2012-02-28 公開日 2012-08-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism. Blood, 120, 2012
4DTE	Crystal structure of zebrafish plasminogen activator inhibitor-1 (PAI-1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Serpin peptidase inhibitor, clade E (nexin, ... 著者 Johansen, J.S. 登録日 2012-02-21 公開日 2013-03-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Protein conformational change delayed by steric hindrance from an N-linked glycan. J.Mol.Biol., 425, 2013
4AJU	Crystal structure of the reactive loop cleaved ZPI in P41 space group 分子名称: 1,2-ETHANEDIOL, PROTEIN Z-DEPENDENT PROTEASE INHIBITOR, SULFATE ION 著者 Zhou, A, Yan, Y, Wei, Z. 登録日 2012-02-19 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AJT	The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI) 分子名称: PROTEIN Z-DEPENDENT PROTEASE INHIBITOR 著者 Yan, Y, Zhou, A. 登録日 2012-02-19 公開日 2012-12-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AFX	Crystal structure of the reactive loop cleaved ZPI in I2 space group 分子名称: CALCIUM ION, PHOSPHATE ION, PROTEIN Z DEPENDENT PROTEASE INHIBITOR, ... 著者 Zhou, A, Yan, Y, Wei, Z. 登録日 2012-01-23 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
3UT3	A novel PAI-I inhibitor and its structural mechanism 分子名称: 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione, Plasminogen activator inhibitor 1 著者 Lin, Z.H, Hong, Z.B, Shi, X.L, Hu, L.H, Andreasen, P.A, Huang, M.D. 登録日 2011-11-25 公開日 2013-02-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 A novel PAI-I inhibitor and its structural mechanism To be Published
3T1P	Crystal structure of an alpha-1-antitrypsin trimer 分子名称: Alpha-1-antitrypsin 著者 Huntington, J.A, Yamasaki, M. 登録日 2011-07-22 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Molecular basis of alpha 1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer. EMBO Rep., 12, 2011
3STO	Serpin from the trematode Schistosoma Haematobium 分子名称: Serine protease inhibitor 著者 Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E. 登録日 2011-07-11 公開日 2012-05-30 最終更新日 2013-01-23 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain. Acta Crystallogr.,Sect.D, 68, 2012
3R4L	Human very long half life Plasminogen Activator Inhibitor type-1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasminogen activator inhibitor 1, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Yang, J, Zheng, H, Han, Q, Skrzypczak-Jankun, E, Jankun, J. 登録日 2011-03-17 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure. Int.J.Mol.Med., 29, 2012
3Q02	Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation. 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Plasminogen activator inhibitor 1, ... 著者 Jensen, J.K, Morth, J.P. 登録日 2010-12-15 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability. J.Biol.Chem., 286, 2011
3Q03	Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation. 分子名称: CHLORIDE ION, Plasminogen activator inhibitor 1, ZINC ION 著者 Jensen, J.K, Morth, J.P. 登録日 2010-12-15 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6401 Å) 主引用文献 Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability. J.Biol.Chem., 286, 2011
3PZF	1.75A resolution structure of Serpin-2 from Anopheles gambiae 分子名称: Serpin 2 著者 Lovell, S, Battaile, K.P, An, C, Michel, K. 登録日 2010-12-14 公開日 2011-02-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of native Anopheles gambiae serpin-2, a negative regulator of melanization in mosquitoes. Proteins, 79, 2011
3PB1	Crystal Structure of a Michaelis Complex between Plasminogen Activator Inhibitor-1 and Urokinase-type Plasminogen Activator 分子名称: Plasminogen activator inhibitor 1, Plasminogen activator, urokinase, ... 著者 Lin, Z, Jiang, L, Huang, M, Structure 2 Function Project (S2F) 登録日 2010-10-20 公開日 2010-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1. J.Biol.Chem., 286, 2011
3OZQ	Crystal structure of Serpin48, which is a highly specific serpin in the insect Tenebrio molitor 分子名称: Serpin48 著者 Park, S.H, Piao, S, Ha, N.-C. 登録日 2010-09-27 公開日 2010-10-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional characterization of a highly specific serpin in the insect innate immunity J.Biol.Chem., 286, 2011
2XN3	Crystal structure of thyroxine-binding globulin complexed with mefenamic acid 分子名称: 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID, THYROXINE-BINDING GLOBULIN 著者 Qi, X, Yan, Y, Wei, Z, Zhou, A. 登録日 2010-07-30 公開日 2011-02-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011

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