3Q02

Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.

Summary for 3Q02
Related1B3K 1DB2 1DVM
DescriptorPlasminogen activator inhibitor 1, CHLORIDE ION, ZINC ION, ... (5 entities in total)
Functional Keywordspai-1, active serpin, serine protease inhibitor, metastable conformation, hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P05121
Total number of polymer chains2
Total formula weight85823.85
Authors
Jensen, J.K.,Morth, J.P. (deposition date: 2010-12-15, release date: 2011-06-22, Last modification date: 2017-11-08)
Primary citationAndreasen, P.A.,Bucci, J.C.,Gettins, P.G.,Jensen, J.K.,Morth, J.P.,Nissen, P.,Peterson, C.B.,Thompson, L.C.
Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
J.Biol.Chem., 286:29709-29717, 2011
PubMed: 21697084
DOI: 110.1074/jbc.M111.236554
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation
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PDB entries from 2021-06-09