3R4L

Human very long half life Plasminogen Activator Inhibitor type-1

Summary for 3R4L

Entry DOI	10.2210/pdb3r4l/pdb
Related	1B3K 1DVM 3Q02
Descriptor	Plasminogen activator inhibitor 1, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	serine protease inhibitor, pai-1, very long half life, plasminogen activator inhibitor type 1, carbohydrate, blood clotting
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	43956.20
Authors	Yang, J.,Zheng, H.,Han, Q.,Skrzypczak-Jankun, E.,Jankun, J. (deposition date: 2011-03-17, release date: 2011-11-02, Last modification date: 2023-09-13)
Primary citation	Jankun, J.,Yang, J.,Zheng, H.,Han, F.Q.,Al-Senaidy, A.,Skrzypczak-Jankun, E. Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure. Int.J.Mol.Med., 29:61-64, 2012 Cited by PubMed: 21947232 DOI: 10.3892/ijmm.2011.798 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation