4AFX

Crystal structure of the reactive loop cleaved ZPI in I2 space group

Summary for 4AFX

• Entry DOI: 10.2210/pdb4afx/pdb
• Related: 4AJU
• Descriptor: PROTEIN Z DEPENDENT PROTEASE INHIBITOR, SODIUM ION, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: hydrolase inhibitor, serpin, protein z dependent inhibitor, coagulation
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 48895.98

Authors

Zhou, A.,Yan, Y.,Wei, Z. (deposition date: 2012-01-23, release date: 2013-01-09, Last modification date: 2023-12-20)

• Primary citation: Huang, X.,Yan, Y.,Tu, Y.,Gatti, J.,Broze, G.J.J.,Zhou, A.,Olson, S.T.; Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.; Blood, 120:1726-, 2012; PubMed: 22786881; DOI: 10.1182/BLOOD-2012-03-419598

Experimental method

X-RAY DIFFRACTION (2.09 Å)