4AFX
Crystal structure of the reactive loop cleaved ZPI in I2 space group
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN Z DEPENDENT PROTEASE INHIBITOR | polymer | 387 | 44358.0 | 1 | UniProt (Q9UK55) Pfam (PF00079) | HOMO SAPIENS (HUMAN) | PZ-DEPENDENT PROTEASE INHIBITOR, PZI, SERPIN A10 |
| 2 | B (B) | PROTEIN Z DEPENDENT PROTEASE INHIBITOR | polymer | 36 | 4167.0 | 1 | UniProt (Q9UK55) | HOMO SAPIENS (HUMAN) | PZ-DEPENDENT PROTEASE INHIBITOR, PZI, SERPIN A10 |
| 3 | C, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F, H (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 2 - 387 (UniProt: Q9UK55)
B: 388 - 423 (UniProt: Q9UK55)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Arg 387 | Tyr 408 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ile 395 | Val 416 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48525.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 371.0 | |
| All* | Total formula weight | 48896.0 |
