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8CGH	Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 3) Descriptor: TAR DNA-binding protein 43 Authors: Arseni, D, Ryskeldi-Falcon, B. Deposit date: 2023-02-04 Release date: 2023-08-02 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (2.68 Å) Cite: TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP. Nature, 620, 2023
8CGG	Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2) Descriptor: TAR DNA-binding protein 43 Authors: Arseni, D, Ryskeldi-Falcon, B. Deposit date: 2023-02-04 Release date: 2023-08-02 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP. Nature, 620, 2023
8CG3	Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1) Descriptor: TAR DNA-binding protein 43 Authors: Arseni, D, Ryskeldi-Falcon, B. Deposit date: 2023-02-03 Release date: 2023-08-02 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (2.39 Å) Cite: TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP. Nature, 620, 2023
8CAS	Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial) Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... Authors: Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. Deposit date: 2023-01-24 Release date: 2023-05-24 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
8CAH	Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... Authors: Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. Deposit date: 2023-01-24 Release date: 2023-05-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
8C6J	Human spliceosomal PM5 C* complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Dybkov, O, Kastner, B, Luehrmann, R. Deposit date: 2023-01-12 Release date: 2023-07-12 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins. Sci Adv, 9, 2023
8BY6	Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... Authors: Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. Deposit date: 2022-12-12 Release date: 2024-01-24 Last modified: 2024-01-31 Method: ELECTRON MICROSCOPY (3.19 Å) Cite: Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
8B8S	Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3 Descriptor: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 Authors: Kachariya, N, Sattler, M, Keil, P, Strasser, K. Deposit date: 2022-10-04 Release date: 2022-11-09 Last modified: 2023-02-08 Method: SOLUTION NMR, SOLUTION SCATTERING Cite: Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA. Nucleic Acids Res., 51, 2023
8ANY	Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA Descriptor: 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... Authors: Singh, V, Itoh, Y, Amunts, A. Deposit date: 2022-08-06 Release date: 2023-08-16 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome To Be Published
8A98	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT Descriptor: 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... Authors: Rajan, K.S, Yonath, A, Bashan, A. Deposit date: 2022-06-28 Release date: 2023-10-11 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.46 Å) Cite: Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
8A3W	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE Descriptor: 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, 40S ribosomal protein S2, ... Authors: Rajan, K.S, Yonath, A, Bashan, A. Deposit date: 2022-06-09 Release date: 2023-12-20 Method: ELECTRON MICROSCOPY (2.89 Å) Cite: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE To Be Published
7ZUG	Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain Descriptor: CHLORIDE ION, Heterogeneous nuclear ribonucleoprotein H, N-terminally processed, ... Authors: Winter, N, Kumar, M, Isupov, M.N, Wiener, R. Deposit date: 2022-05-12 Release date: 2023-05-24 Method: X-RAY DIFFRACTION (1.075 Å) Cite: Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain To Be Published
7ZNK	Structure of an endogenous human TREX complex bound to mRNA Descriptor: RNA, Spliceosome RNA helicase DDX39B, THO complex subunit 1, ... Authors: Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. Deposit date: 2022-04-21 Release date: 2023-05-03 Last modified: 2023-05-24 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: mRNA recognition and packaging by the human transcription-export complex. Nature, 616, 2023
7ZNJ	Structure of an ALYREF-exon junction complex hexamer Descriptor: Eukaryotic initiation factor 4A-III, N-terminally processed, MAGNESIUM ION, ... Authors: Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. Deposit date: 2022-04-21 Release date: 2023-04-12 Last modified: 2023-05-24 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: mRNA recognition and packaging by the human transcription-export complex. Nature, 616, 2023
7ZJ2	Amyloid fibril (in vitro) from full-length hnRNPA1 protein Descriptor: Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 Authors: Sharma, K, Banerjee, S, Schmidt, M, Faendrich, M. Deposit date: 2022-04-08 Release date: 2023-08-02 Last modified: 2023-08-09 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril. J.Mol.Biol., 435, 2023
7ZIR	Cryo-EM structure of hnRNPDL amyloid fibrils Descriptor: Heterogeneous nuclear ribonucleoprotein D-like Authors: Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S. Deposit date: 2022-04-08 Release date: 2022-12-28 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3. Nat Commun, 14, 2023
7ZHR	Complex structure of drosophila Unr CSD789 and pAbp RRM3 Descriptor: Polyadenylate-binding protein, Upstream of N-ras, isoform A Authors: Hollmann, N.M, Jagtap, P.K.A, Hennig, J. Deposit date: 2022-04-07 Release date: 2022-12-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Upstream of N-Ras C-terminal cold shock domains mediate poly(A) specificity in a novel RNA recognition mode and bind poly(A) binding protein. Nucleic Acids Res., 51, 2023
7ZEZ	Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 Descriptor: Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ... Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2023-05-03 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEY	Complex Cyp33-RRM : MLL1-PHD3 Descriptor: MLL cleavage product N320, Peptidyl-prolyl cis-trans isomerase E, ZINC ION Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEX	Complex Cyp33-RRMdelta alpha : UAAUGUCG RNA Descriptor: Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3') Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-05-04 Last modified: 2023-05-03 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEW	Complex Cyp33-RRM : AAUAAA RNA Descriptor: Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*AP*AP*UP*AP*AP*A)-3') Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2023-05-03 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEV	Free form of extended Cyp33-RRM Descriptor: Peptidyl-prolyl cis-trans isomerase E Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2023-05-03 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZAP	Solution structure of RBM39 RRM1 bound to U1 snRNA stem loop 3 Descriptor: RNA-binding protein 39, U1 snRNA SL3 Authors: Campagne, S, Allain, F.H. Deposit date: 2022-03-22 Release date: 2023-03-29 Last modified: 2023-09-20 Method: SOLUTION NMR Cite: Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39. Nat Commun, 14, 2023
7Z3X	Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*T)-3'), DNA (5'-D(P*GP*TP*())-3'), ... Authors: Ni, X, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2022-03-02 Release date: 2022-11-09 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA To Be Published
7YEX	Structure of MmIGF2BP3 in complex with 8-mer RNA Descriptor: Insulin-like growth factor 2 mRNA-binding protein 3, RNA (5'-R(P*CP*AP*CP*AP*CP*AP*CP*A)-3') Authors: Li, X.J, Wu, B.X. Deposit date: 2022-07-06 Release date: 2023-07-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of MmIGF2BP3 in complex with 8-mer RNA To Be Published

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