7ZIR

Cryo-EM structure of hnRNPDL amyloid fibrils

Summary for 7ZIR

Entry DOI	10.2210/pdb7zir/pdb
EMDB information	14738
Descriptor	Heterogeneous nuclear ribonucleoprotein D-like (2 entities in total)
Functional Keywords	amyloid, protein aggregation, alternative splicing, exon, prion-like, lgmd1g, cryoem structure, rna binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	5
Total formula weight	229021.33
Authors	Garcia-Pardo, J.,Chaves-Sanjuan, A.,Bartolome-Nafria, A.,Gil-Garcia, M.,Visentin, C.,Bolognesi, M.,Ricagno, S.,Ventura, S. (deposition date: 2022-04-08, release date: 2022-12-28, Last modification date: 2023-12-13)
Primary citation	Garcia-Pardo, J.,Bartolome-Nafria, A.,Chaves-Sanjuan, A.,Gil-Garcia, M.,Visentin, C.,Bolognesi, M.,Ricagno, S.,Ventura, S. Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3. Nat Commun, 14:239-239, 2023 Cited by PubMed: 36646699 DOI: 10.1038/s41467-023-35854-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation