7ZIR

Cryo-EM structure of hnRNPDL amyloid fibrils

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (C, A, E, D, B)	Heterogeneous nuclear ribonucleoprotein D-like	polymer	407	45804.3	5	UniProt (O14979) Pfam (PF00076)	Homo sapiens (human)	hnRNP D-like,hnRNP DL,AU-rich element RNA-binding factor,JKT41-binding protein,Protein laAUF1
2	F, G, H, I, J (C, A, E, D, B)	water	water		18.0	50	Chemie (HOH)

Sequence modifications

C, A, E, D, B: 121 - 420 (UniProt: O14979)

PDB	External Database	Details
Met 14	-	initiating methionine
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
Gly 21	-	expression tag
Ser 22	-	expression tag
Leu 23	-	expression tag
Gln 24	-	expression tag
Asp 25	-	expression tag
Ser 26	-	expression tag
Glu 27	-	expression tag
Val 28	-	expression tag
Asn 29	-	expression tag
Gln 30	-	expression tag
Glu 31	-	expression tag
Ala 32	-	expression tag
Lys 33	-	expression tag
Pro 34	-	expression tag
Glu 35	-	expression tag
Val 36	-	expression tag
Lys 37	-	expression tag
Pro 38	-	expression tag
Glu 39	-	expression tag
Val 40	-	expression tag
Lys 41	-	expression tag
Pro 42	-	expression tag
Glu 43	-	expression tag
Thr 44	-	expression tag
His 45	-	expression tag
Ile 46	-	expression tag
Asn 47	-	expression tag
Leu 48	-	expression tag
Lys 49	-	expression tag
Val 50	-	expression tag
Ser 51	-	expression tag
Asp 52	-	expression tag
Gly 53	-	expression tag
Ser 54	-	expression tag
Ser 55	-	expression tag
Glu 56	-	expression tag
Ile 57	-	expression tag
Phe 58	-	expression tag
Phe 59	-	expression tag
Lys 60	-	expression tag
Ile 61	-	expression tag
Lys 62	-	expression tag
Lys 63	-	expression tag
Thr 64	-	expression tag
Thr 65	-	expression tag
Pro 66	-	expression tag
Leu 67	-	expression tag
Arg 68	-	expression tag
Arg 69	-	expression tag
Leu 70	-	expression tag
Met 71	-	expression tag
Glu 72	-	expression tag
Ala 73	-	expression tag
Phe 74	-	expression tag
Ala 75	-	expression tag
Lys 76	-	expression tag
Arg 77	-	expression tag
Gln 78	-	expression tag
Gly 79	-	expression tag
Lys 80	-	expression tag
Glu 81	-	expression tag
Met 82	-	expression tag
Asp 83	-	expression tag
Ser 84	-	expression tag
Leu 85	-	expression tag
Thr 86	-	expression tag
Phe 87	-	expression tag
Leu 88	-	expression tag
Tyr 89	-	expression tag
Asp 90	-	expression tag
Gly 91	-	expression tag
Ile 92	-	expression tag
Glu 93	-	expression tag
Ile 94	-	expression tag
Gln 95	-	expression tag
Ala 96	-	expression tag
Asp 97	-	expression tag
Gln 98	-	expression tag
Thr 99	-	expression tag
Pro 100	-	expression tag
Glu 101	-	expression tag
Asp 102	-	expression tag
Leu 103	-	expression tag
Asp 104	-	expression tag
Met 105	-	expression tag
Glu 106	-	expression tag
Asp 107	-	expression tag
Asn 108	-	expression tag
Asp 109	-	expression tag
Ile 110	-	expression tag
Ile 111	-	expression tag
Glu 112	-	expression tag
Ala 113	-	expression tag
His 114	-	expression tag
Arg 115	-	expression tag
Glu 116	-	expression tag
Gln 117	-	expression tag
Ile 118	-	expression tag
Gly 119	-	expression tag
Gly 120	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	229021.3
All*	Total formula weight	229021.3

*Water molecules are not included.