PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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1H02	Human Insulin-like growth factor; SRS Daresbury data 分子名称: INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE 著者 Brzozowski, A.M, Dodson, E.J, Dodson, G.G, Murshudov, G, Verma, C, Turkenburg, J.P, De Bree, F.M, Dauter, Z. 登録日 2002-06-11 公開日 2002-07-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin Biochemistry, 41, 2002
1HIT	Receptor binding redefined by a structural switch in a mutant Human Insulin 分子名称: INSULIN 著者 Hua, Q.X, Kochoyan, M, Weiss, M.A. 登録日 1992-02-28 公開日 1994-01-31 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Receptor binding redefined by a structural switch in a mutant human insulin. Nature, 354, 1991
1HIQ	PARADOXICAL STRUCTURE AND FUNCTION IN A MUTANT HUMAN INSULIN ASSOCIATED WITH DIABETES MELLITUS 分子名称: INSULIN 著者 Hua, Q.X, Shoelson, S.E, Inouye, K, Weiss, M.A. 登録日 1993-03-05 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus. Proc.Natl.Acad.Sci.USA, 90, 1993
1HUI	INSULIN MUTANT (B1, B10, B16, B27)GLU, DES-B30, NMR, 25 STRUCTURES 分子名称: INSULIN 著者 Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. 登録日 1996-03-29 公開日 1997-03-12 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 Solution structure of an engineered insulin monomer at neutral pH. Biochemistry, 35, 1996
1HLS	NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16) 分子名称: INSULIN 著者 Ludvigsen, S, Kaarsholm, N.C. 登録日 1995-06-28 公開日 1995-09-15 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr-->His, as determined by nuclear magnetic resonance spectroscopy. Biochemistry, 33, 1994
1HO0	NEW B-CHAIN MUTANT OF BOVINE INSULIN 分子名称: INSULIN 著者 Dupradeau, F.Y, Richard, T, Le Flem, G, Oulyadi, H, Prigent, Y, Monti, J.P. 登録日 2000-12-08 公開日 2000-12-20 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 A new B-chain mutant of insulin: comparison with the insulin crystal structure and role of sulfonate groups in the B-chain structure J.Pept.Res., 60, 2002
1IZA	ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN 分子名称: INSULIN 著者 Xiao, B, Dodson, G.G. 登録日 1992-10-16 公開日 1993-10-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin. J.Mol.Biol., 228, 1992
1IGL	SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS 分子名称: INSULIN-LIKE GROWTH FACTOR II 著者 Torres, A.M, Forbes, B.E, Aplin, S.E, Wallace, J.C, Francis, G.L, Norton, R.S. 登録日 1994-12-29 公開日 1995-02-14 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions. J.Mol.Biol., 248, 1995
1IOH	INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES 分子名称: PROTEIN (INSULIN PRECURSOR) 著者 Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. 登録日 1998-08-13 公開日 1999-01-13 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix. J.Mol.Biol., 284, 1998
1IZB	ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN 分子名称: INSULIN, ZINC ION 著者 Xiao, B, Dodson, G.G. 登録日 1992-10-16 公開日 1993-10-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin. J.Mol.Biol., 228, 1992
1IOG	INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES 分子名称: PROTEIN (INSULIN PRECURSOR) 著者 Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. 登録日 1998-08-13 公開日 1999-01-13 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix. J.Mol.Biol., 284, 1998
1J73	Crystal structure of an unstable insulin analog with native activity. 分子名称: ZINC ION, insulin a, insulin b 著者 Wan, Z, Zhao, M, Nakagawa, S, Jia, W, Weiss, M.A. 登録日 2001-05-15 公開日 2001-05-30 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. J.Mol.Biol., 315, 2002
1IMX	1.8 Angstrom crystal structure of IGF-1 分子名称: BROMIDE ION, Insulin-like Growth Factor 1A, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE 著者 Vajdos, F.F, Ultsch, M, Schaffer, M.L, Deshayes, K.D, Liu, J, Skelton, N.J, de Vos, A.M. 登録日 2001-05-11 公開日 2001-09-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions. Biochemistry, 40, 2001
1JCO	Solution structure of the monomeric [Thr(B27)->Pro,Pro(B28)->Thr] insulin mutant (PT insulin) 分子名称: Insulin A chain, Insulin B chain 著者 Keller, D, Clausen, R, Josefsen, K, Led, J.J. 登録日 2001-06-11 公開日 2001-10-03 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 Flexibility and bioactivity of insulin: an NMR investigation of the solution structure and folding of an unusually flexible human insulin mutant with increased biological activity. Biochemistry, 40, 2001
4BS3	Bovin insulin structure determined by in situ crystal analysis and sulfur-SAD phasing at room temperature 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Pinker, F, Stirnimann, C, Sauter, C, Olieric, V. 登録日 2013-06-06 公開日 2013-07-17 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Chipx: A Novel Microfluidic Chip for Counter- Diffusion Crystallization of Biomolecules and in Situ Crystal Analysis at Room Temperature J.Cryst.Growth, 13, 2013
2HH4	NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures 分子名称: insulin A chain, insulin B chain 著者 Hua, Q.X, Nakagawa, S, Hu, S.Q, Jia, W, Weiss, M.A. 登録日 2006-06-27 公開日 2006-07-18 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Toward the Active Conformation of Insulin: Stereospecific modulation of a structural switch in the B chain. J.Biol.Chem., 281, 2006
2HHO	NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures 分子名称: Insulin A chain, Insulin B chain 著者 Hua, Q.X, Nakagawa, S, Hu, S.Q, Jia, W, Weiss, M.A. 登録日 2006-06-28 公開日 2006-07-18 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Toward the Active Conformation of Insulin: Stereospecific modulation of a structural switch in the B chain. J.Biol.Chem., 281, 2006
2INS	THE STRUCTURE OF DES-PHE B1 BOVINE INSULIN 分子名称: DES-PHE B1 INSULIN (CHAIN A), DES-PHE B1 INSULIN (CHAIN B), ZINC ION 著者 Smith, G.D, Duax, W.L, Dodson, E.J, Dodson, G.G, Degraaf, R.A.G, Reynolds, C.D. 登録日 1982-05-10 公開日 1982-08-05 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Structure of Des-Phe B1 Bovine Insulin Acta Crystallogr.,Sect.B, 38, 1982
4CXL	Human insulin analogue (D-ProB8)-insulin 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN 著者 Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. 登録日 2014-04-07 公開日 2014-05-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry, 53, 2014
4CXN	Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. 登録日 2014-04-07 公開日 2014-05-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry, 53, 2014
4CY7	Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form II 分子名称: ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. 登録日 2014-04-10 公開日 2014-05-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry, 53, 2014
2JMN	NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures 分子名称: Insulin A chain, Insulin B chain 著者 Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. 登録日 2006-11-21 公開日 2006-12-05 最終更新日 2023-12-20 実験手法 SOLUTION NMR 主引用文献 Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J.Mol.Biol., 264, 1996
2JV1	NMR structure of human insulin monomer in 35% CD3CN zinc free, 50 structures 分子名称: Insulin 著者 Bocian, W, Kozerski, L. 登録日 2007-09-11 公開日 2007-12-11 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structure of human insulin monomer in water/acetonitrile solution. J.Biomol.Nmr, 40, 2008
2JUU	allo-ThrA3 DKP-insulin 分子名称: Insulin A chain, Insulin B chain 著者 Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. 登録日 2007-09-03 公開日 2007-10-16 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007
2JUM	ThrA3-DKP-insulin 分子名称: Insulin A chain, Insulin B chain 著者 Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. 登録日 2007-08-31 公開日 2007-10-16 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007

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