1HIQ

PARADOXICAL STRUCTURE AND FUNCTION IN A MUTANT HUMAN INSULIN ASSOCIATED WITH DIABETES MELLITUS

Summary for 1HIQ

DescriptorINSULIN (2 entities in total)
Functional Keywordshormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5757.56
Authors
Hua, Q.X.,Shoelson, S.E.,Inouye, K.,Weiss, M.A. (deposition date: 1993-03-05, release date: 1994-01-31, Last modification date: 2017-11-29)
Primary citation
Hua, Q.X.,Shoelson, S.E.,Inouye, K.,Weiss, M.A.
Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus.
Proc.Natl.Acad.Sci.USA, 90:582-586, 1993
PubMed: 8421693 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.90.2.582
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers37.8%5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 1hiq
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Molmil generated image of 1hiq
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Molmil generated image of 1hiq
rotated about y axis by 90°