1HIT

Receptor binding redefined by a structural switch in a mutant Human Insulin

Summary for 1HIT

DescriptorINSULIN (2 entities in total)
Functional Keywordshormone
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight5727.53
Authors
Hua, Q.X.,Kochoyan, M.,Weiss, M.A. (deposition date: 1992-02-28, release date: 1994-01-31, Last modification date: 2011-07-13)
Primary citation
Hua, Q.X.,Shoelson, S.E.,Kochoyan, M.,Weiss, M.A.
Receptor binding redefined by a structural switch in a mutant human insulin.
Nature, 354:238-241, 1991
PubMed: 1961250 (PDB entries with the same primary citation)
DOI: 10.1038/354238a0
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers1312.1%12.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 1hit
no rotation
Molmil generated image of 1hit
rotated about x axis by 90°
Molmil generated image of 1hit
rotated about y axis by 90°