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1HIT

Receptor binding redefined by a structural switch in a mutant Human Insulin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
INSULINpolymer212383.71UniProt (P01308)Homo sapiens (human)
2B
(B)
INSULINpolymer303343.81UniProt (P01308)
Pfam (PF00049)
Homo sapiens (human)
Sequence modifications
B: 1 - 30 (UniProt: P01308)
PDBExternal DatabaseDetails
Gly 24Phe 48engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight5727.5
All*Total formula weight5727.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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