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4AJZ
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Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-21
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4CXL
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Human insulin analogue (D-ProB8)-insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN
著者Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L.
登録日2014-04-07
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53, 2014
1XDA
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STRUCTURE OF INSULIN
分子名称: CHLORIDE ION, FATTY ACID ACYLATED INSULIN, MYRISTIC ACID, ...
著者Whittingham, J.L, Havelund, S, Jonassen, I.
登録日1996-12-18
公開日1997-07-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a prolonged-acting insulin with albumin-binding properties.
Biochemistry, 36, 1997
4CXN
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Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L.
登録日2014-04-07
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53, 2014
4CY7
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Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form II
分子名称: ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L.
登録日2014-04-10
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53, 2014
4AK0
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BU of 4ak0 by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-21
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
1WAV
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BU of 1wav by Molmil
CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN
分子名称: INSULIN, PHENOL, ZINC ION
著者Liang, D.-C, Ding, J.-H, Chang, W.-R, Wan, Z.-L.
登録日1996-02-28
公開日1997-02-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular replacement study on form-B monoclinic crystal of insulin.
Sci.China, Ser.C: Life Sci., 39, 1996
4A7E
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X-ray crystal structure of porcine insulin flash-cooled at high pressure
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Burkhardt, A, Warmer, M, Panneerselvam, S, Wagner, A, Reimer, R, Hohenberg, H, Meents, A.
登録日2011-11-14
公開日2011-11-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.856 Å)
主引用文献Fast High-Pressure Freezing of Protein Crystals in Their Mother Liquor
Acta Crystallogr.,Sect.F, 68, 2012
1W8P
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BU of 1w8p by Molmil
Structural properties of the B25Tyr-NMe-B26Phe insulin mutant.
分子名称: INSULIN A-CHAIN, INSULIN B-CHAIN, PHENOL, ...
著者Zakowa, L, Au-Alvarez, O, Dodson, E.J, Dodson, G.G, Brzozowski, A.M.
登録日2004-09-24
公開日2005-02-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Towards the Insulin-Igf-I Intermediate Structures: Functional and Structural Properties of the B25Tyr-Nme-B26Phe Insulin Mutant.
Biochemistry, 43, 2004
1VKT
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BU of 1vkt by Molmil
HUMAN INSULIN TWO DISULFIDE MODEL, NMR, 10 STRUCTURES
分子名称: INSULIN
著者Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A.
登録日1996-10-14
公開日1997-04-01
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
J.Mol.Biol., 264, 1996
1XGL
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BU of 1xgl by Molmil
HUMAN INSULIN DISULFIDE ISOMER, NMR, 10 STRUCTURES
分子名称: INSULIN
著者Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A.
登録日1996-10-10
公開日1997-04-01
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structure of a protein in a kinetic trap.
Nat.Struct.Biol., 2, 1995
1ZEG
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BU of 1zeg by Molmil
STRUCTURE OF B28 ASP INSULIN IN COMPLEX WITH PHENOL
分子名称: CHLORIDE ION, INSULIN, PHENOL, ...
著者Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G.
登録日1998-05-01
公開日1998-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
4BS3
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BU of 4bs3 by Molmil
Bovin insulin structure determined by in situ crystal analysis and sulfur-SAD phasing at room temperature
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Pinker, F, Stirnimann, C, Sauter, C, Olieric, V.
登録日2013-06-06
公開日2013-07-17
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Chipx: A Novel Microfluidic Chip for Counter- Diffusion Crystallization of Biomolecules and in Situ Crystal Analysis at Room Temperature
J.Cryst.Growth, 13, 2013
1XW7
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BU of 1xw7 by Molmil
Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama
分子名称: CHLORIDE ION, Insulin, PHENOL, ...
著者Wan, Z.L, Huang, K, Xu, B, Chu, Y.C, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A.
登録日2004-10-29
公開日2005-04-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin wakayama
Biochemistry, 44, 2005
1ZNJ
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BU of 1znj by Molmil
INSULIN, MONOCLINIC CRYSTAL FORM
分子名称: CHLORIDE ION, INSULIN, PHENOL, ...
著者Turkenburg, M.G.W, Whittingham, J.L, Turkenburg, J.P, Dodson, G.G, Derewenda, U, Smith, G.D, Dodson, E.J, Derewenda, Z.S, Xiao, B.
登録日1997-09-23
公開日1998-01-28
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure Determination and Refinement of Two Crystal Forms of Native Insulins
To be Published
1ZEH
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BU of 1zeh by Molmil
STRUCTURE OF INSULIN
分子名称: CHLORIDE ION, INSULIN, M-CRESOL, ...
著者Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G.
登録日1998-05-01
公開日1998-12-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
4E7V
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BU of 4e7v by Molmil
The structure of R6 bovine insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Harris, P, Frankaer, C.G, Knudsen, M.V.
登録日2012-03-19
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
4EWX
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BU of 4ewx by Molmil
Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-04-28
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4EXX
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BU of 4exx by Molmil
Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-05-01
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
4EY1
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BU of 4ey1 by Molmil
Human Insulin
分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
著者Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R.
登録日2012-05-01
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.471 Å)
主引用文献Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
1ZNI
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BU of 1zni by Molmil
INSULIN
分子名称: CHLORIDE ION, INSULIN, ZINC ION
著者Turkenburg, M.G.W, Whittingham, J.L, Dodson, G.G, Dodson, E.J, Xiao, B, Bentley, G.A.
登録日1997-09-23
公開日1998-01-28
最終更新日2018-07-04
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
1ZEI
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CROSS-LINKED B28 ASP INSULIN
分子名称: CHLORIDE ION, INSULIN, M-CRESOL, ...
著者Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G.
登録日1998-07-14
公開日1999-02-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
4E7T
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BU of 4e7t by Molmil
The structure of T6 bovine insulin
分子名称: Insulin A chain, Insulin B chain, ZINC ION
著者Harris, P, Frankaer, C.G, Knudsen, M.V.
登録日2012-03-19
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy.
Acta Crystallogr.,Sect.D, 68, 2012
1EV3
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Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer
分子名称: CHLORIDE ION, INSULIN, M-CRESOL, ...
著者Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H.
登録日2000-04-19
公開日2000-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献R6 hexameric insulin complexed with m-cresol or resorcinol.
Acta Crystallogr.,Sect.D, 56, 2000
5T7R
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BU of 5t7r by Molmil
A6-A11 trans-dicarba human insulin
分子名称: Insulin A chain, Insulin B chain
著者Menting, J.G, Lawrence, M.C, Robinson, A.J, Forbes, B.E.
登録日2016-09-05
公開日2017-12-06
最終更新日2019-06-19
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity.
Sci Rep, 7, 2017

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