4EWX

Human Insulin

Summary for 4EWX

Related4EWW 4EWZ 4EX0 4EX1
DescriptorInsulin A chain, Insulin B chain, ZINC ION, ... (5 entities in total)
Functional Keywordshormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11837.03
Authors
Favero-Retto, M.P.,Palmieri, L.C.,Lima, L.M.T.R. (deposition date: 2012-04-28, release date: 2013-05-01, Last modification date: 2017-11-15)
Primary citation
Favero-Retto, M.P.,Palmieri, L.C.,Souza, T.A.,Almeida, F.C.,Lima, L.M.
Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85:1112-1121, 2013
PubMed: 23692694 (PDB entries with the same primary citation)
DOI: 10.1016/j.ejpb.2013.05.005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.201 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2501201.1%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

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Molmil generated image of 4ewx
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4ewx.pdb1.gz [114.93 KB])