3H8N
 
 | | Crystal Structure Analysis of KIR2DS4 | | Descriptor: | Killer cell immunoglobulin-like receptor 2DS4 | | Authors: | Graef, T, Bushnell, D.A, Parham, P. | | Deposit date: | 2009-04-29 | | Release date: | 2009-10-20 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.
J.Exp.Med., 206, 2009
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3WYR
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1UCT
 | | Crystal structure of the extracellular fragment of Fc alpha Receptor I (CD89) | | Descriptor: | Immunoglobulin alpha Fc receptor | | Authors: | Ding, Y, Xu, G, Yang, M, Zhang, W, Rao, Z. | | Deposit date: | 2003-04-21 | | Release date: | 2003-07-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of the Ectodomain of Human Fc{alpha}RI.
J.Biol.Chem., 278, 2003
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1NKR
 | | INHIBITORY RECEPTOR (P58-CL42) FOR HUMAN NATURAL KILLER CELLS | | Descriptor: | P58-CL42 KIR | | Authors: | Fan, Q.R, Mosyak, L, Winter, C.C, Wagtmann, N, Long, E.O, Wiley, D.C. | | Deposit date: | 1998-06-24 | | Release date: | 1998-11-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors.
Nature, 389, 1997
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4ESK
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4ETY
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1OVZ
 | | Crystal structure of human FcaRI | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Herr, A.B, Ballister, E.R, Bjorkman, P.J. | | Deposit date: | 2003-03-27 | | Release date: | 2003-05-27 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Insights into IgA-mediated immune responses from the crystal structures of human Fc-alpha-RI and its complex with IgA1-Fc
Nature, 423, 2003
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1M4K
 | | Crystal structure of the human natural killer cell activator receptor KIR2DS2 (CD158j) | | Descriptor: | 1,2-ETHANEDIOL, KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DS2, SULFATE ION | | Authors: | Saulquin, X, Gastinel, L.N, Vivier, E. | | Deposit date: | 2002-07-03 | | Release date: | 2003-04-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the human natural killer cell
activating receptor KIR2DS2 (CD158j)
J.EXP.MED., 197, 2003
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4LL9
 | | Crystal structure of D3D4 domain of the LILRB1 molecule | | Descriptor: | IODIDE ION, Leukocyte immunoglobulin-like receptor subfamily B member 1 | | Authors: | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | Deposit date: | 2013-07-09 | | Release date: | 2013-09-11 | | Last modified: | 2013-11-06 | | Method: | X-RAY DIFFRACTION (2.686 Å) | | Cite: | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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4LLA
 | | Crystal structure of D3D4 domain of the LILRB2 molecule | | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 2 | | Authors: | Nam, G, Shi, Y, Ryu, M, Wang, Q, Song, H, Liu, J, Yan, J, Qi, J, Gao, G.F. | | Deposit date: | 2013-07-09 | | Release date: | 2013-09-11 | | Last modified: | 2013-11-06 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Crystal structures of the two membrane-proximal Ig-like domains (D3D4) of LILRB1/B2: alternative models for their involvement in peptide-HLA binding
Protein Cell, 4, 2013
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1B6U
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8TUI
 | | Crystal structure of Fab-Lirilumab bound to KIR2DL3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell immunoglobulin-like receptor 2DL3, Lirilumab Fab Heavy Chain, ... | | Authors: | Lorig-Roach, N, DuBois, R.M. | | Deposit date: | 2023-08-16 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab.
Sci Rep, 14, 2024
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2DLI
 | | KILLER IMMUNOGLOBULIN RECEPTOR 2DL2,TRIGONAL FORM | | Descriptor: | PROTEIN (MHC CLASS I NK CELL RECEPTOR PRECURSOR) | | Authors: | Sun, P.D, Snyder, G.A. | | Deposit date: | 1999-03-08 | | Release date: | 2000-01-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2
Proc.Natl.Acad.Sci.USA, 96, 1999
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2CKN
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2EC8
 | | Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor | | Authors: | Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J. | | Deposit date: | 2007-02-11 | | Release date: | 2007-08-07 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
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2DL2
 | | KILLER IMMUNOGLOBULIN RECEPTOR 2DL2 | | Descriptor: | PROTEIN (MHC CLASS I NK CELL RECEPTOR PRECURSOR (P58 NATURAL KILLER CELL RECEPTOR CLONE CL-43)) | | Authors: | Sun, P, Snyder, G. | | Deposit date: | 1999-03-08 | | Release date: | 1999-03-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2
Proc.Natl.Acad.Sci.USA, 96, 1999
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2CR3
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3S36
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3S35
 | | Structural basis for the function of two anti-VEGF receptor antibodies | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6.64 Fab heavy chain, ... | | Authors: | Franklin, M.C. | | Deposit date: | 2011-05-17 | | Release date: | 2011-08-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
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3S37
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3CHN
 | | Solution structure of human secretory IgA1 | | Descriptor: | Ig alpha-1 chain C region, Immunoglobulin kappa light chain, Secretory component | | Authors: | Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J. | | Deposit date: | 2008-03-10 | | Release date: | 2008-12-30 | | Last modified: | 2024-02-21 | | Method: | SOLUTION SCATTERING | | Cite: | Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.
Mucosal Immunol, 2, 2009
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6XJA
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1EFX
 | | STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3 | | Descriptor: | BETA-2-MICROGLOBULIN, HLA-CW3 (HEAVY CHAIN), NATURAL KILLER CELL RECEPTOR KIR2DL2, ... | | Authors: | Boyington, J.C, Motyka, S.A, Schuck, P, Brooks, A.G, Sun, P.D. | | Deposit date: | 2000-02-10 | | Release date: | 2000-06-14 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.
Nature, 405, 2000
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1N26
 | | Crystal Structure of the extra-cellular domains of Human Interleukin-6 Receptor alpha chain | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Varghese, J.N, Moritz, R.L, Lou, M.-Z, van Donkelaar, A, Ji, H, Ivancic, N, Branson, K.M, Hall, N.E, Simpson, R.J. | | Deposit date: | 2002-10-22 | | Release date: | 2002-12-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the extracellular domains of the human interleukin-6 receptor alpha-chain.
Proc.Natl.Acad.Sci.USA, 99, 2002
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3VH8
 | | KIR3DL1 in complex with HLA-B*5701 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Vivian, J.P, Rossjohn, J. | | Deposit date: | 2011-08-24 | | Release date: | 2011-10-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B
Nature, 479, 2011
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