8TUI
Crystal structure of Fab-Lirilumab bound to KIR2DL3
Summary for 8TUI
| Entry DOI | 10.2210/pdb8tui/pdb |
| Descriptor | Lirilumab Fab Heavy Chain, Lirilumab Fab Light chain, Killer cell immunoglobulin-like receptor 2DL3, ... (5 entities in total) |
| Functional Keywords | antibody, kir2dl3, complex, lirilumab, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 3 |
| Total formula weight | 80791.30 |
| Authors | Lorig-Roach, N.,DuBois, R.M. (deposition date: 2023-08-16, release date: 2023-12-06, Last modification date: 2024-01-24) |
| Primary citation | Lorig-Roach, N.,Harpell, N.M.,DuBois, R.M. Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab. Sci Rep, 14:742-742, 2024 Cited by PubMed: 38185735DOI: 10.1038/s41598-023-50262-6 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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