8TUI
Crystal structure of Fab-Lirilumab bound to KIR2DL3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | Lirilumab Fab Heavy Chain | polymer | 265 | 27793.8 | 1 | Homo sapiens | ||
2 | L | Lirilumab Fab Light chain | polymer | 214 | 23548.2 | 1 | Homo sapiens | ||
3 | A | Killer cell immunoglobulin-like receptor 2DL3 | polymer | 257 | 28189.1 | 1 | UniProt (P43628) Pfam (PF00047) In PDB | Homo sapiens (human) | CD158 antigen-like family member B2,KIR-023GB,Killer inhibitory receptor cl 2-3,NKAT2a,NKAT2b,Natural killer-associated transcript 2,NKAT-2,p58 natural killer cell receptor clone CL-6,p58 NK receptor CL-6,p58.2 MHC class-I-specific NK receptor |
4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1260.2 | 1 | In PDB GlyTouCan (G45889JQ) | |||
5 | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 1 - 224 (UniProt: P43628)
PDB | External Database | Details |
---|---|---|
Ala 225 | - | expression tag |
Ala 226 | - | expression tag |
Ala 227 | - | expression tag |
Glu 228 | - | expression tag |
Gln 229 | - | expression tag |
Lys 230 | - | expression tag |
Leu 231 | - | expression tag |
Ile 232 | - | expression tag |
Ser 233 | - | expression tag |
Glu 234 | - | expression tag |
Glu 235 | - | expression tag |
Asp 236 | - | expression tag |
Leu 237 | - | expression tag |
Asn 238 | - | expression tag |
Leu 239 | - | expression tag |
Asp 240 | - | expression tag |
Leu 241 | - | expression tag |
Val 242 | - | expression tag |
Pro 243 | - | expression tag |
Arg 244 | - | expression tag |
Gly 245 | - | expression tag |
Ser 246 | - | expression tag |
Ser 247 | - | expression tag |
Ser 248 | - | expression tag |
His 249 | - | expression tag |
His 250 | - | expression tag |
His 251 | - | expression tag |
His 252 | - | expression tag |
His 253 | - | expression tag |
His 254 | - | expression tag |
Ser 255 | - | expression tag |
Ser 256 | - | expression tag |
Gly 257 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 79531.1 | |
Branched | Number of molecules | 1 |
Total formula weight | 1260.2 | |
All* | Total formula weight | 80791.3 |