3H8N

Crystal Structure Analysis of KIR2DS4

Summary for 3H8N

• Entry DOI: 10.2210/pdb3h8n/pdb
• Related: 1efx 1im9
• Descriptor: Killer cell immunoglobulin-like receptor 2DS4 (2 entities in total)
• Functional Keywords: ligand-binding domains, cell membrane, disulfide bond, glycoprotein, immunoglobulin domain, membrane, polymorphism, receptor, transmembrane, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type I membrane protein: P43632
• Total number of polymer chains: 1
• Total formula weight: 21534.24

Authors

Graef, T.,Bushnell, D.A.,Parham, P. (deposition date: 2009-04-29, release date: 2009-10-20, Last modification date: 2023-09-06)

• Primary citation: Graef, T.,Moesta, A.K.,Norman, P.J.,Abi-Rached, L.,Vago, L.,Older Aguilar, A.M.,Gleimer, M.,Hammond, J.A.,Guethlein, L.A.,Bushnell, D.A.,Robinson, P.J.,Parham, P.; KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.; J.Exp.Med., 206:2557-2572, 2009; PubMed: 19858347; DOI: 10.1084/jem.20091010

Experimental method

X-RAY DIFFRACTION (2.5 Å)