3S36
Structural basis for the function of two anti-VEGF receptor antibodies
Summary for 3S36
Entry DOI | 10.2210/pdb3s36/pdb |
Related | 3S34 3S37 |
Descriptor | 1121B light chain, 1121B heavy chain, Vascular endothelial growth factor receptor 2 (3 entities in total) |
Functional Keywords | antibody, kdr, vegf receptor, cancer, immune system-transferase complex, immune system/transferase |
Biological source | Mus musculus, Homo sapiens (mouse, human) More |
Cellular location | Cell junction . Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted . Isoform 3: Secreted: P35968 |
Total number of polymer chains | 3 |
Total formula weight | 60074.27 |
Authors | Franklin, M.C. (deposition date: 2011-05-17, release date: 2011-08-24, Last modification date: 2017-11-08) |
Primary citation | Franklin, M.C.,Navarro, E.C.,Wang, Y.,Patel, S.,Singh, P.,Zhang, Y.,Persaud, K.,Bari, A.,Griffith, H.,Shen, L.,Balderes, P.,Kussie, P. The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies. Structure, 19:1097-1107, 2011 Cited by PubMed: 21827946DOI: 10.1016/j.str.2011.01.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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