1EBA
 
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1EBP
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2XYC
 | | CRYSTAL STRUCTURE OF NCAM2 IGIV-FN3I | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NEURAL CELL ADHESION MOLECULE 2, ... | | Authors: | Kulahin, N, Rasmussen, K.K, Kristensen, O, Berezin, V, Bock, E, Walmod, P.S, Gajhede, M. | | Deposit date: | 2010-11-17 | | Release date: | 2011-02-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Structural Model and Trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule.
Structure, 19, 2011
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1ERN
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5FMV
 | | Crystal structure of human CD45 extracellular region, domains d1-d4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, SULFATE ION | | Authors: | Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. | | Deposit date: | 2015-11-09 | | Release date: | 2016-03-23 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
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5FN6
 | | Crystal structure of human CD45 extracellular region, domains d1-d3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C | | Authors: | Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. | | Deposit date: | 2015-11-10 | | Release date: | 2016-03-23 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17, 2016
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1F6F
 | | CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN OVINE PLACENTAL LACTOGEN AND THE EXTRACELLULAR DOMAIN OF THE RAT PROLACTIN RECEPTOR | | Descriptor: | PLACENTAL LACTOGEN, PROLACTIN RECEPTOR | | Authors: | Elkins, P.A, Christinger, H.W, Sandowski, Y, Sakal, E, Gertler, A, De Vos, A.M, Kossiakoff, A.A. | | Deposit date: | 2000-06-21 | | Release date: | 2000-07-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
Nat.Struct.Biol., 7, 2000
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5FM5
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1HWH
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1HWG
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5I99
 | | Crystal structure of mouse CNTN3 Ig5-Fn2 domains | | Descriptor: | Contactin-3, GLYCEROL | | Authors: | Nikolaienko, R.M, Bouyain, S. | | Deposit date: | 2016-02-19 | | Release date: | 2016-08-31 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.
J.Biol.Chem., 291, 2016
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5J7C
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5J12
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1I1R
 | | CRYSTAL STRUCTURE OF A CYTOKINE/RECEPTOR COMPLEX | | Descriptor: | INTERLEUKIN-6 RECEPTOR BETA CHAIN, VIRAL IL-6 | | Authors: | Chow, D, He, X, Snow, A.L, Rose-John, S, Garcia, K.C. | | Deposit date: | 2001-02-02 | | Release date: | 2001-03-28 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of an extracellular gp130 cytokine receptor signaling complex.
Science, 291, 2001
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5J11
 | | Structure of human TSLP in complex with TSLPR and IL-7Ralpha | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, ... | | Authors: | Verstraete, K, Savvides, S.N. | | Deposit date: | 2016-03-28 | | Release date: | 2017-04-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma.
Nat Commun, 8, 2017
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1KF9
 | | PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF THE EXTRACELLULAR DOMAIN OF ITS RECEPTOR | | Descriptor: | EXTRACELLULAR DOMAIN HUMAN GROWTH HORMONE RECEPTOR (1-238), PHAGE DISPLAY DERIVED VARIANT HUMAN GROWTH HORMONE | | Authors: | Schiffer, C.A, Ultsch, M, Walsh, S, Somers, W, De Vos, A.M, Kossiakoff, A.A. | | Deposit date: | 2001-11-19 | | Release date: | 2002-11-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of a Phage Display Derived Variant of Human Growth Hormone Complexed to Two Copies of the Extracellular Domain of its Receptor: Evidence for Strong Structural Coupling between Receptor Binding Sites
J.Mol.Biol., 316, 2002
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3UP1
 | | Crystal structure of the unliganded human interleukin-7 receptor extracellular domain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | McElroy, C.A, Holland, P.J, Walsh, S.T.R. | | Deposit date: | 2011-11-17 | | Release date: | 2012-02-08 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural reorganization of the interleukin-7 signaling complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4ZXB
 | | Structure of the human insulin receptor ectodomain, IRDeltabeta construct, in complex with four Fab molecules | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Croll, T, Smith, B.J, Margetts, M.B, Whittaker, J, Weiss, M.A, Ward, C.W, Lawrence, M.C. | | Deposit date: | 2015-05-20 | | Release date: | 2016-02-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain.
Structure, 24, 2016
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5C6P
 | | protein C | | Descriptor: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, protein C, protein D | | Authors: | Lu, M. | | Deposit date: | 2015-06-23 | | Release date: | 2015-09-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the blockade of MATE multidrug efflux pumps.
Nat Commun, 6, 2015
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4BK5
 | | crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample) | | Descriptor: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | Deposit date: | 2013-04-22 | | Release date: | 2013-07-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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4BKA
 | | crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 | | Descriptor: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | Deposit date: | 2013-04-23 | | Release date: | 2013-07-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (5.3 Å) | | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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4BKF
 | | crystal structure of the human EphA4 ectodomain in complex with human ephrinB3 | | Descriptor: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-B3 | | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | Deposit date: | 2013-04-24 | | Release date: | 2013-07-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (4.65 Å) | | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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4BK4
 | | crystal structure of the human EphA4 ectodomain | | Descriptor: | EPHRIN TYPE-A RECEPTOR 4 | | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | Deposit date: | 2013-04-22 | | Release date: | 2013-07-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.65 Å) | | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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4BQ6
 | | Crystal structure of the RGMB-NEO1 complex form 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NEOGENIN, RGM DOMAIN FAMILY MEMBER B | | Authors: | Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | | Deposit date: | 2013-05-30 | | Release date: | 2013-06-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
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4BQ7
 | | Crystal structure of the RGMB-Neo1 complex form 2 | | Descriptor: | NEOGENIN, RGM DOMAIN FAMILY MEMBER B | | Authors: | Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | | Deposit date: | 2013-05-30 | | Release date: | 2013-06-12 | | Last modified: | 2019-04-03 | | Method: | X-RAY DIFFRACTION (6.601 Å) | | Cite: | Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
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