3UP1

Crystal structure of the unliganded human interleukin-7 receptor extracellular domain

Summary for 3UP1

• Entry DOI: 10.2210/pdb3up1/pdb
• Descriptor: Interleukin-7 receptor subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose, ... (7 entities in total)
• Functional Keywords: cytokine receptor, fibronectin type 3 fold, membrane and soluble, glycosylation, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 53629.05

Authors

McElroy, C.A.,Holland, P.J.,Walsh, S.T.R. (deposition date: 2011-11-17, release date: 2012-02-08, Last modification date: 2022-12-21)

• Primary citation: McElroy, C.A.,Holland, P.J.,Zhao, P.,Lim, J.M.,Wells, L.,Eisenstein, E.,Walsh, S.T.; Structural reorganization of the interleukin-7 signaling complex.; Proc.Natl.Acad.Sci.USA, 109:2503-2508, 2012; PubMed: 22308406; DOI: 10.1073/pnas.1116582109

Experimental method

X-RAY DIFFRACTION (2.15 Å)