3UP1
Crystal structure of the unliganded human interleukin-7 receptor extracellular domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interleukin-7 receptor subunit alpha | polymer | 223 | 25691.0 | 2 | UniProt (P16871) Pfam (PF18447) Pfam (PF00041) | Homo sapiens (human) | IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CDw127 |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, I (A, B) | alpha-L-fucopyranose | non-polymer | 164.2 | 2 | Chemie (FUC) | |||
| 4 | F, G, K, L, M (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | H, N, O, P (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | J (B) | 2-acetamido-2-deoxy-beta-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (NGA) | |||
| 7 | Q, R (A, B) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 219 (UniProt: P16871)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Val 118 | Ile 138 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51382.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1398.2 | |
| All* | Total formula weight | 53629.1 |
