PDB: 413 件ウェブページステータス検索Chemie searchBIRD

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5VMN	Crystal structure of grouper iridovirus GIV66 分子名称: 1,2-ETHANEDIOL, Bak protein, NITRATE ION 著者 Banjara, S, Kvansakul, M. 登録日 2017-04-27 公開日 2018-03-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim. J. Biol. Chem., 293, 2018
5W62	Crystal structure of mouse BAX monomer 分子名称: Apoptosis regulator BAX, SULFATE ION 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E, Luo, C.S. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.196 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W5X	Crystal structure of BAXP168G in complex with an activating antibody 分子名称: 1,2-ETHANEDIOL, 3C10 Fab' heavy chain, 3C10 Fab' light chain, ... 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W5Z	Crystal structure of BAXP168G in complex with an activating antibody at high resolution 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3C10 Fab heavy chain, ... 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W60	Crystal structure of BAXP168G monomer cryo-protected with ethylene glycol 分子名称: Apoptosis regulator BAX, SULFATE ION 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W61	Crystal structure of BAXP168G monomer co-crystallized with glycerol 分子名称: Apoptosis regulator BAX 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W63	Crystal structure of channel catfish BAX 分子名称: 1,2-ETHANEDIOL, Apoptosis regulator bax, SULFATE ION 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E, Luo, C.S. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.436 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W89	Crystal structure of human Mcl-1 in complex with modified Bim BH3 peptide SAH-MS1-18 分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, modified Bim BH3 peptide SAH-MS1-18 著者 Rezaei Araghi, R, Jenson, J.M, Grant, R.A, Keating, A.E. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W8F	Crystal structure of human Mcl-1 in complex with modified Bim BH3 peptide SAH-MS1-14 分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, modified Bim BH3 peptide SAH-MS1-14 著者 Rezaei Araghi, R, Jenson, J.M, Grant, R.A, Keating, A.E. 登録日 2017-06-21 公開日 2018-01-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5WHH	Crystal Structure of Bcl-2-related protein A1 in complex with stapled peptide (AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2) 分子名称: (AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2), Bcl-2-related protein A1, CHLORIDE ION 著者 Seo, H.-S, Dhe-Paganon, S. 登録日 2017-07-17 公開日 2018-01-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor. Structure, 26, 2018
1AF3	RAT BCL-XL AN APOPTOSIS INHIBITORY PROTEIN 分子名称: APOPTOSIS REGULATOR BCL-X 著者 Aritomi, M, Kunishima, N, Inohara, N, Ishibashi, Y, Ohta, S, Morikawa, K. 登録日 1997-03-21 公開日 1997-07-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family. J.Biol.Chem., 272, 1997
1BXL	STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: BAK PEPTIDE, BCL-XL 著者 Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W. 登録日 1996-10-16 公開日 1997-10-29 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis. Science, 275, 1997
6YLI	Crystal structure of human bcl-xL bound to trichoplax adhaerens trBak BH3 分子名称: Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1, SULFATE ION 著者 D Sa, J, Banjara, S, Kvansakul, M. 登録日 2020-04-07 公開日 2021-03-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis. Sci Adv, 6, 2020
8U27	Bcl-2-xL complexed with compound 35 分子名称: Apoptosis regulator Bcl-2, Bcl-2-like protein 1 chimera, propan-2-yl {4-[(5S)-1-(4-bromobenzoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}carbamate 著者 Rizo, J, Pan, Y.-Z. 登録日 2023-09-05 公開日 2023-09-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural insights for selective disruption of Beclin 1 binding to Bcl-2. Commun Biol, 6, 2023
7CA4	The Crystal Structure of human Bcl-2-like protein 1 from Biortus 分子名称: Bcl-2-like protein 1, SULFATE ION 著者 Wang, F, Lv, Z, Lin, D, Huang, Y. 登録日 2020-06-08 公開日 2020-07-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Crystal Structure of human Bcl-2-like protein 1 from Biortus. To Be Published
8XP5	The Crystal Structure of p53/BCL-xL fusion complex from Biortus. 分子名称: Bcl-2-like protein 1,Cellular tumor antigen p53, ZINC ION 著者 Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. 登録日 2024-01-03 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The Crystal Structure of p53/BCL-xL fusion complex from Biortus. To Be Published
8WLS	Bcl-xL in complex with HBx BH3 delta C peptide 分子名称: Bcl-2-like protein 1, Protein X 著者 Kobayashi, N, Nagata, T, Kusunoki, H. 登録日 2023-10-01 公開日 2024-03-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Insights into the Interaction between the C-Terminal-Deleted BH3-like Motif Peptide of Hepatitis B Virus X Protein and Bcl-x L. Biochemistry, 63, 2024
7WJH	Crystal structure of Bcl-xL bound to the BH3 domain of human Pxt1 分子名称: Bcl-2-like protein 1, MAGNESIUM ION, Peroxisomal testis-specific protein 1, ... 著者 Lim, D, Ku, B. 登録日 2022-01-06 公開日 2022-09-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1. Biochem.Biophys.Res.Commun., 625, 2022
7XGF	Crystal structure of BCL-xL in complex with computationally designed inhibitor protein 分子名称: BCL-xL, BCL-xL and MCL-1 dual inhibitor 2 著者 Oh, B.-H, Kim, S. 登録日 2022-04-04 公開日 2022-07-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Computational design of an apoptogenic protein that binds BCL-xL and MCL-1 simultaneously and potently. Comput Struct Biotechnol J, 20, 2022
7XGG	Crystal structure of BCL-xL in complex with computationally designed inhibitor protein 分子名称: BCL-xL and MCL-1 dual inhibitor, Bcl-2-like protein 1 著者 Oh, B.-H, Kim, S. 登録日 2022-04-04 公開日 2022-07-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Computational design of an apoptogenic protein that binds BCL-xL and MCL-1 simultaneously and potently. Comput Struct Biotechnol J, 20, 2022
7JGV	CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH COMPOUND 1620116, CRYSTAL FORM 2 分子名称: 6-[(8E)-8-{2-[4-(benzylcarbamoyl)-1,3-thiazol-2-yl]hydrazinylidene}-5,6,7,8-tetrahydronaphthalen-2-yl]-3-(2-phenylethoxy)pyridine-2-carboxylic acid, Bcl-2-like protein 1 著者 Lee, M, Fairlie, W.D, Smith, B.J, Lee, E.F. 登録日 2020-07-19 公開日 2021-02-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2. Acs Infect Dis., 7, 2021
7JGW	Crystal structure of BCL-XL in complex with COMPOUND 1620116, CRYSTAL FORM 1 分子名称: 6-[(8E)-8-{2-[4-(benzylcarbamoyl)-1,3-thiazol-2-yl]hydrazinylidene}-5,6,7,8-tetrahydronaphthalen-2-yl]-3-(2-phenylethoxy)pyridine-2-carboxylic acid, Bcl-2-like protein 1 著者 Lee, M, Fairlie, W.D, Smith, B.J, Lee, E.F. 登録日 2020-07-19 公開日 2021-02-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2. Acs Infect Dis., 7, 2021
1GJH	HUMAN BCL-2, ISOFORM 2 分子名称: PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN) 著者 Petros, A.M, Medek, A, Nettesheim, D.G, Kim, D.H, Yoon, H.S, Swift, K, Matayoshi, E.D, Oltersdorf, T, Fesik, S.W. 登録日 2001-05-31 公開日 2001-06-13 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of the antiapoptotic protein bcl-2. Proc.Natl.Acad.Sci.USA, 98, 2001
1G5J	COMPLEX OF BCL-XL WITH PEPTIDE FROM BAD 分子名称: APOPTOSIS REGULATOR BCL-X, BAD PROTEIN 著者 Petros, A.M, Nettesheim, D.G, Wang, Y, Olejniczak, E.T, Meadows, R.P, Mack, J, Swift, K, Matayoshi, E.D, Zhang, H, Thompson, C.B, Fesik, S.W. 登録日 2000-11-01 公開日 2001-02-07 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies. Protein Sci., 9, 2000
1G5M	HUMAN BCL-2, ISOFORM 1 分子名称: PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN) 著者 Petros, A.M, Medek, A, Nettesheim, D.G, Kim, D.H, Yoon, H.S, Swift, K, Matayoshi, E.D, Oltersdorf, T, Fesik, S.W. 登録日 2000-11-01 公開日 2001-03-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the antiapoptotic protein bcl-2. Proc.Natl.Acad.Sci.USA, 98, 2001

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