5WHH

Crystal Structure of Bcl-2-related protein A1 in complex with stapled peptide (AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2)

Summary for 5WHH

• Entry DOI: 10.2210/pdb5whh/pdb
• Descriptor: Bcl-2-related protein A1, (AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2), CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: apoptosis, stapled peptide
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: Q16548
• Total number of polymer chains: 2
• Total formula weight: 20689.99

Authors

Seo, H.-S.,Dhe-Paganon, S. (deposition date: 2017-07-17, release date: 2018-01-17, Last modification date: 2023-11-15)

• Primary citation: Harvey, E.P.,Seo, H.S.,Guerra, R.M.,Bird, G.H.,Dhe-Paganon, S.,Walensky, L.D.; Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.; Structure, 26:153-160.e4, 2018; PubMed: 29276033; DOI: 10.1016/j.str.2017.11.016

Experimental method

X-RAY DIFFRACTION (2.38 Å)