5WHH

Crystal Structure of Bcl-2-related protein A1 in complex with stapled peptide (AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Bcl-2-related protein A1	polymer	161	18596.1	1	UniProt (Q16548) Pfam (PF00452) In PDB	Homo sapiens (Human)	Bcl-2-like protein 5,Bcl2-L-5,Hemopoietic-specific early response protein,Protein BFL-1,Protein GRS
2	B	(AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2)	polymer	16	2058.5	1		synthetic construct
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4		water	water		18.0	53	Chemie (HOH)

Sequence modifications

A: 1 - 151 (UniProt: Q16548)

PDB	External Database	Details
Met -9	-	initiating methionine
Gly -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ser 4	Cys 4	engineered mutation
Ser 19	Cys 19	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	20654.5
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	20690.0

*Water molecules are not included.