4YD8
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7QD6
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![BU of 7qd6 by Molmil](/molmil-images/mine/7qd6) | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with strand-transfer like DNA product | Descriptor: | IR71st non transferred strand, IR71st transferred strand, Transposase for transposon Tn4430 | Authors: | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | Deposit date: | 2021-11-26 | Release date: | 2022-10-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insight into Tn3 family transposition mechanism. Nat Commun, 13, 2022
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4YEC
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7UCF
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8PC6
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![BU of 8pc6 by Molmil](/molmil-images/mine/8pc6) | H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Koutna, E, Kouba, T, Veverka, V. | Deposit date: | 2023-06-09 | Release date: | 2023-08-16 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
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7QD5
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![BU of 7qd5 by Molmil](/molmil-images/mine/7qd5) | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with 48 bp long transposon end DNA | Descriptor: | IR48 DNA substrate, non transferred strand, IR48 transferred strand, ... | Authors: | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | Deposit date: | 2021-11-26 | Release date: | 2022-10-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insight into Tn3 family transposition mechanism. Nat Commun, 13, 2022
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7UCE
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7Y27
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![BU of 7y27 by Molmil](/molmil-images/mine/7y27) | Cryo-EM structure of the SST-14-bound SSTR2-miniGq-scFv16 complex | Descriptor: | CHOLESTEROL, Engineered Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Chen, S, Zheng, S. | Deposit date: | 2022-06-09 | Release date: | 2022-10-19 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Molecular basis for the selective G protein signaling of somatostatin receptors. Nat.Chem.Biol., 19, 2023
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4RWS
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![BU of 4rws by Molmil](/molmil-images/mine/4rws) | Crystal structure of CXCR4 and viral chemokine antagonist vMIP-II complex (PSI Community Target) | Descriptor: | C-X-C chemokine receptor type 4/Endolysin chimeric protein, Viral macrophage inflammatory protein 2 | Authors: | Qin, L, Kufareva, I, Holden, L, Wang, C, Zheng, Y, Wu, H, Fenalti, G, Han, G.W, Cherezov, V, Abagyan, R, Stevens, R.C, Handel, T.M, GPCR Network (GPCR) | Deposit date: | 2014-12-05 | Release date: | 2015-02-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science, 347, 2015
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7Y26
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![BU of 7y26 by Molmil](/molmil-images/mine/7y26) | Cryo-EM structure of the octreotide-bound SSTR2-miniGq-scFv16 complex | Descriptor: | Engineered Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Chen, S, Zheng, S. | Deposit date: | 2022-06-09 | Release date: | 2022-10-19 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for the selective G protein signaling of somatostatin receptors. Nat.Chem.Biol., 19, 2023
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3QMS
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![BU of 3qms by Molmil](/molmil-images/mine/3qms) | Crystal structure of the mutant T159V,V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | Deposit date: | 2011-02-05 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
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6YZ2
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![BU of 6yz2 by Molmil](/molmil-images/mine/6yz2) | Full length Open-form Sodium Channel NavMs F208L | Descriptor: | DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... | Authors: | Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A. | Deposit date: | 2020-05-06 | Release date: | 2020-11-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Cannabidiol interactions with voltage-gated sodium channels. Elife, 9, 2020
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7XT7
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![BU of 7xt7 by Molmil](/molmil-images/mine/7xt7) | RNA polymerase II elongation complex transcribing a nucleosome (EC49B) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-16 | Release date: | 2022-10-12 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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7XTI
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![BU of 7xti by Molmil](/molmil-images/mine/7xti) | RNA polymerase II elongation complex transcribing a nucleosome (EC58hex) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-17 | Release date: | 2022-10-12 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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8P0Z
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![BU of 8p0z by Molmil](/molmil-images/mine/8p0z) | AP01-S2.3 - a variant of a redesigned transferrin receptor apical domain | Descriptor: | BORIC ACID, SODIUM ION, Transferrin receptor protein 1, ... | Authors: | Oberdorfer, G, Grill, B, Bjelic, S, Stoll, D. | Deposit date: | 2023-05-11 | Release date: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Affinity Maturated Transferrin Receptor Apical Domain Blocks Machupo Virus Glycoprotein Binding. J.Mol.Biol., 435, 2023
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4WWU
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![BU of 4wwu by Molmil](/molmil-images/mine/4wwu) | Structure of Mex67:Mtr2 | Descriptor: | ZINC ION, mRNA export factor MEX67, mRNA transport regulator MTR2 | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-12 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.301 Å) | Cite: | Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface. Nucleic Acids Res., 43, 2015
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4RP3
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![BU of 4rp3 by Molmil](/molmil-images/mine/4rp3) | Crystal Structure of the L27 Domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster bound to a potassium ion (space group P212121) | Descriptor: | CHLORIDE ION, Disks large 1 tumor suppressor protein, FORMIC ACID, ... | Authors: | Ghosh, A, Ramagopal, U, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-10-29 | Release date: | 2014-11-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module. Biochemistry, 57, 2018
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3QF0
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![BU of 3qf0 by Molmil](/molmil-images/mine/3qf0) | Crystal structure of the mutant T159V,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP | Descriptor: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | Authors: | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | Deposit date: | 2011-01-20 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
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6QCI
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![BU of 6qci by Molmil](/molmil-images/mine/6qci) | Structure of XIAP-BIR1 V86E mutant | Descriptor: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ... | Authors: | Sorrentino, L, Cossu, F, Milani, M, Mastrangelo, E. | Deposit date: | 2018-12-28 | Release date: | 2019-05-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1. Chemistryopen, 8, 2019
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4WV5
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8PBB
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![BU of 8pbb by Molmil](/molmil-images/mine/8pbb) | CHAPSO treated partial catalytic component (comprising only AnfD & AnfK, lacking AnfG and FeFeco) of iron nitrogenase from Rhodobacter capsulatus | Descriptor: | FE(8)-S(7) CLUSTER, Nitrogenase iron-iron protein, beta subunit, ... | Authors: | Schmidt, F.V, Schulz, L, Zarzycki, J, Prinz, S, Erb, T.J, Rebelein, J.G. | Deposit date: | 2023-06-09 | Release date: | 2023-10-04 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | Structural insights into the iron nitrogenase complex. Nat.Struct.Mol.Biol., 31, 2024
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6QCK
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![BU of 6qck by Molmil](/molmil-images/mine/6qck) | 17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB262 | Descriptor: | 17-beta-hydroxysteroid dehydrogenase 14, 2-[2-(1,3-benzodioxol-2-yl)ethyl]benzoic acid, DIMETHYL SULFOXIDE, ... | Authors: | Bertoletti, N, Marchais-Oberwinkler, S, Heine, A, Klebe, G. | Deposit date: | 2018-12-28 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Mutational and structural studies uncover crucial amino acids determining activity and stability of 17 beta-HSD14. J.Steroid Biochem.Mol.Biol., 189, 2019
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7NYH
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7NZ1
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7O1I
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![BU of 7o1i by Molmil](/molmil-images/mine/7o1i) | Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A mutant | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, GLYCEROL, ... | Authors: | Dalwani, S, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2021-03-29 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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